Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CERT1 | Q9Y5P4 | 3/20 | 0.45 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.44 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.44 |
| ▸ | MMP2 | P08253 | 10/20 | 0.44 |
| ▸ | MMP9 | P14780 | 3/20 | 0.44 |
| ▸ | MMP1 | P03956 | 3/20 | 0.44 |
| ▸ | MMP3 | P08254 | 3/20 | 0.44 |
| ▸ | MMP14 | P50281 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | NAAA | Q02083 | 2/20 | 0.43 |
| ▸ | MMP12 | P39900 | 1/20 | 0.43 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.42 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3242852 | 0.86 | GABBR2 (0.54) | GABBR2GABBR1MMP2MMP9MMP1 | |
| SCHEMBL4403980 | 0.86 | GABBR2 (0.54) | GABBR2GABBR1MMP2MMP9MMP1 | |
| SCHEMBL27688433 | 0.86 | GABBR2 (0.54) | GABBR2GABBR1MMP2MMP9MMP1 | |
| SCHEMBL7663044 | 0.84 | GABBR2 (0.56) | GABBR2GABBR1MMP2MMP9MAPT | |
| SCHEMBL2289954 | 0.80 | GABBR2 (0.58) | GABBR2GABBR1MMP2MMP9MAPT | |
| Bicarbonate SCHEMBL10711244 | 0.78 | NAAA (0.49) | CERT1NAAACYSLTR2CYSLTR1 | |
| Malonic Acid SCHEMBL28316448 | 0.76 | NAAA (0.48) | CERT1MMP2MMP9MMP1MMP3 | |
| SCHEMBL14359785 | 0.76 | GABBR2 (0.66) | GABBR2GABBR1MAPT | |
| SCHEMBL8846325 | 0.76 | CYSLTR2 (0.63) | CYSLTR2CYSLTR1 | |
| SCHEMBL10354176 | 0.76 | CYSLTR2 (0.59) | CYSLTR2CYSLTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5292884-A | Cyclic hydroxamic acids | BIOMIDE INVESTMENT LIMITED PARTNERSHIP (US) | 1994-03-08 | — | — | US | disclosed |
| US-5234933-A | Antiflammatory agents, enzyme inhibitors | BOARD OF GOVERNORS OF WAYNE STATE UNIVERSITY AND VANDERBILT UNIVERSITY (US) | 1993-08-10 | — | — | US | disclosed |
| WO-1993008803-A1 | CYCLIC HYDROXAMIC ACIDS | BOARD OF GOVERNORS OF WAYNE STATE UNIVERSITY (US) | 1993-05-13 | — | — | WO | disclosed |