Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R | Q15722 | 1/20 | 0.49 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.49 |
| ▸ | LTA4H | P09960 | 12/20 | 0.47 |
| ▸ | MAOB | P27338 | 5/20 | 0.44 |
| ▸ | HRH1 | P35367 | 1/20 | 0.43 |
| ▸ | BCHE | P06276 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10493530 | 0.83 | LTB4R (0.49) | LTB4RLTB4R2LTA4HMAOB | |
| SCHEMBL6539246 | 0.82 | MAPK1 (0.52) | LTB4RLTB4R2MAOB | |
| SCHEMBL542829 | 0.76 | LTB4R (0.60) | LTB4RLTB4R2MAOB | |
| SCHEMBL3098374 | 0.75 | MTNR1A (0.58) | LTA4HHRH1 | |
| SCHEMBL6538645 | 0.74 | LTB4R (0.47) | LTB4RLTB4R2MAOB | |
| SCHEMBL7552353 | 0.74 | LTA4H (0.64) | LTA4HACHE | |
| SCHEMBL26210242 | 0.74 | ALDH1A1 (0.56) | — | |
| SCHEMBL7141067 | 0.73 | LTA4H (0.67) | LTA4H | |
| Hydrochloric Acid SCHEMBL8415688 | 0.73 | ALDH1A1 (0.55) | — | |
| SCHEMBL16421292 | 0.72 | LSS (0.54) | LTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0589018-A1 | AMINES AS INHIBITORS OF SQUALENE SYNTHASE | ZENECA LIMITED (GB) | 1994-03-30 | — | — | EP | disclosed |
| WO-1993020807-A1 | AMINES AS INHIBITORS OF SQUALENE SYNTHASE | ZENECA LIMITED (GB) | 1993-10-28 | — | — | WO | disclosed |