Sugi Predict

Sugi Predict / Compounds / Biotin

Biotin

Biotin

SCHEMBL9328971

C=CCNc1cn([C@H]2C[C@H](O)[C@@H](COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O2)c(=O)[nH]c1=O.O=C(O)CCCC[C@@H]1SC[C@@H]2NC(=O)N[C@@H]21

nearest known ligand 0.46

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Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
▸ F2 P00734 2/20 0.46
▸ TYMS P04818 2/20 0.41
▸ TDP1 Q9NUW8 3/20 0.40
▸ MEN1 O00255 1/20 0.40
▸ ABL1 P00519 1/20 0.40
▸ LMNA P02545 1/20 0.40
▸ PKM P14618 1/20 0.40
▸ IDE P14735 1/20 0.40
▸ MAPK1 P28482 1/20 0.40
▸ KMT2A Q03164 1/20 0.40
▸ RIN1 Q13671 1/20 0.40
▸ L3MBTL1 Q9Y468 1/20 0.40
▸ POLB P06746 2/20 0.40
▸ HLCS P50747 1/20 0.40
▸ POLA1 P09884 1/20 0.39
▸ POLD1 P28340 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Biotin SCHEMBL9489122 0.85 F2 (0.48) F2TDP1MEN1ABL1LMNA
Biotin SCHEMBL381578 0.84 DUT (0.52) F2TDP1POLA1
SCHEMBL6130170 0.83 POLB (0.54) TYMSPOLBPOLA1POLD1
SCHEMBL5685965 0.82 F2 (0.47) F2POLBHLCSPOLA1POLD1
SCHEMBL29627228 0.81 PLCD1 (0.47) F2TYMSPOLBHLCS
SCHEMBL20129499 0.81 PLCD1 (0.49) F2TYMSTDP1HLCS
SCHEMBL29426309 0.80 PLCD1 (0.49) F2TYMSTDP1HLCS
SCHEMBL6129083 0.79 POLB (0.52) TYMSPOLBPOLA1POLD1
SCHEMBL6129081 0.79 POLB (0.52) TYMSPOLBPOLA1POLD1
SCHEMBL9004512 0.79 F2 (0.43) F2POLBHLCSPOLA1POLD1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0122614-B1 KIT FOR TERMINALLY CHEMICALLY LABELING DNA ENZO BIOCHEM, INC. (US) 1993-07-14 — — EP claimed
EP-0122614-A2 Kit for terminally chemically labeling DNA ENZO BIOCHEM, INC. (US) 1984-10-24 — — EP claimed
EP-0133473-B1 In vivo labelling of polynucleotide sequences ENZO BIOCHEM INC (US) 1994-03-23 — — EP disclosed
EP-0122614-B1 KIT FOR TERMINALLY CHEMICALLY LABELING DNA ENZO BIOCHEM, INC. (US) 1993-07-14 — — EP disclosed
US-4987065-A GENETIC ENGINEERING ENZO BIOCHEM, INC. (US) 1991-01-22 — — US disclosed
US-4803297-A Carbamic acid ester useful for preparing a nucleic acid probe CETUS CORPORATION (US) 1989-02-07 — — US disclosed
US-4754065-A NONRADIOACTIVE LABELING CETUS CORPORATION (US) 1988-06-28 — — US disclosed
US-4751313-A NONRADIOACTIVE LABELING CETUS CORPORATION (US) 1988-06-14 — — US disclosed
US-4719176-A Enzyme-free diagnostic binding reagents KLOTZ IRVING M (US) 1988-01-12 — — US disclosed
US-4705886-A Precursor to nucleic acid probe CETUS CORPORATION (US) 1987-11-10 — — US disclosed
US-4617261-A Process for labeling nucleic acids and hybridization probes CETUS CORPORATION (US) 1986-10-14 — — US disclosed
US-4582789-A CONTAINING ALKYLATING INTERCALATION MOIETY CETUS CORPORATION (US) 1986-04-15 — — US disclosed
EP-0156287-A2 Process for labeling nucleic acids using psoralen derivatives CETUS CORPORATION (US) 1985-10-02 — — EP disclosed
EP-0133473-A2 In vivo labelling of polynucleotide sequences ENZO BIOCHEM, INC. (US) 1985-02-27 — — EP disclosed
EP-0124124-A2 Method and materials useful for the analysis and detection of genetic material ENZO BIOCHEM, INC. (US) 1984-11-07 — — EP disclosed
EP-0122614-A2 Kit for terminally chemically labeling DNA ENZO BIOCHEM, INC. (US) 1984-10-24 — — EP disclosed