Metacresol

Metacresol

SCHEMBL9329205

C=O.CNc1cccc(O)c1.Cc1cccc(O)c1

nearest known ligand 0.61

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACHE P22303 1/20 0.61
RAPGEF4 Q8WZA2 1/20 0.50
ALDH1A1 P00352 3/20 0.49
CYP1A2 P05177 2/20 0.49
MAPK1 P28482 1/20 0.48
GAA P10253 2/20 0.47
MMP1 P03956 1/20 0.46
MMP2 P08253 1/20 0.46
MMP9 P14780 1/20 0.46
NLRP3 Q96P20 1/20 0.45
HSD17B10 Q99714 2/20 0.44
HDAC6 Q9UBN7 1/20 0.44
CYP3A4 P08684 1/20 0.44
TSHR P16473 1/20 0.44
CYP2C19 P33261 1/20 0.44
RAB9A P51151 3/20 0.43
MAPT P10636 3/20 0.43
SMN1; SMN2 Q16637 2/20 0.43
MEN1 O00255 2/20 0.43
KMT2A Q03164 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Formaldehyde SCHEMBL9774394 0.91 RAPGEF4 (0.53) ACHERAPGEF4ALDH1A1CYP1A2MAPK1
Formaldehyde SCHEMBL9774158 0.91 ALDH1A1 (0.57) ACHERAPGEF4ALDH1A1CYP1A2MAPK1
Phenol SCHEMBL9773973 0.85 TSHR (0.57) RAPGEF4ALDH1A1CYP1A2MAPK1MMP1
Metacresol SCHEMBL502469 0.84 ACHE (0.85) ACHERAPGEF4ALDH1A1CYP1A2MAPK1
SCHEMBL29807871 0.84
SCHEMBL54893 0.84
Hydrochloric Acid SCHEMBL22689426 0.82 CYP3A4 (0.56) ACHERAPGEF4ALDH1A1CYP1A2MAPK1
Bromide SCHEMBL15020875 0.82 CYP3A4 (0.56) ACHERAPGEF4ALDH1A1CYP1A2MAPK1
Metacresol SCHEMBL8393169 0.82 ACHE (0.81) ACHERAPGEF4ALDH1A1CYP1A2MAPK1
Phenol SCHEMBL6881606 0.81 NPSR1 (0.57) ACHERAPGEF4ALDH1A1CYP1A2GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0298704-B1 Adhesive composition for fibrous materials and process of its preparation BRIDGESTONE CORP (JP) 1994-03-23 EP disclosed
US-5075415-A ADHESIVE COMPOSITION FOR FIBROUS MATERIALS BASED ON PHENOL-AMINOPHENOL-FORMALDEHYDE CONDENSATION PRODUCTS BRIDGESTONE CORPORATION (JP) 1991-12-24 US disclosed
EP-0298704-A2 Adhesive composition for fibrous materials and process of its preparation Bridgestone Corporation (JP) 1989-01-11 EP disclosed