Formaldehyde

Formaldehyde

SCHEMBL9774158

C=O.CNc1cccc(O)c1

nearest known ligand 0.57

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.57
CYP1A2 P05177 3/20 0.57
CYP3A4 P08684 4/20 0.52
TSHR P16473 1/20 0.52
HDAC6 Q9UBN7 1/20 0.52
KMT2A Q03164 4/20 0.48
MEN1 O00255 2/20 0.48
RAPGEF4 Q8WZA2 1/20 0.48
BRAF P15056 3/20 0.47
HSD17B10 Q99714 2/20 0.46
CA12 O43570 1/20 0.46
CA2 P00918 1/20 0.46
LMNA P02545 1/20 0.46
CA5A P35218 1/20 0.46
CA9 Q16790 1/20 0.46
CA14 Q9ULX7 1/20 0.46
CA5B Q9Y2D0 1/20 0.46
HSD17B2 P37059 1/20 0.45
MAPK1 P28482 2/20 0.44
USP2 O75604 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phenol SCHEMBL9773973 0.94 TSHR (0.57) ALDH1A1CYP1A2CYP3A4TSHRHDAC6
SCHEMBL29807871 0.93
SCHEMBL54893 0.93
Bromide SCHEMBL15020875 0.91 CYP3A4 (0.56) ALDH1A1CYP1A2CYP3A4TSHRHDAC6
Hydrochloric Acid SCHEMBL22689426 0.91 CYP3A4 (0.56) ALDH1A1CYP1A2CYP3A4TSHRHDAC6
Metacresol SCHEMBL9329205 0.91 ACHE (0.61) ALDH1A1CYP1A2CYP3A4TSHRHDAC6
Formaldehyde SCHEMBL9774394 0.89 RAPGEF4 (0.53) ALDH1A1CYP1A2CYP3A4TSHRHDAC6
1-Hydroxy-3-Methoxybenzene SCHEMBL9773981 0.86 MEN1 (0.53) ALDH1A1CYP1A2CYP3A4TSHRKMT2A
Formaldehyde SCHEMBL10583252 0.85 TRPA1 (0.53) ALDH1A1CYP1A2CYP3A4TSHRHDAC6
Ethylamine SCHEMBL2480009 0.83 KMT2A (0.48) ALDH1A1CYP1A2CYP3A4TSHRHDAC6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5075415-A ADHESIVE COMPOSITION FOR FIBROUS MATERIALS BASED ON PHENOL-AMINOPHENOL-FORMALDEHYDE CONDENSATION PRODUCTS BRIDGESTONE CORPORATION (JP) 1991-12-24 US disclosed
EP-0298704-A2 Adhesive composition for fibrous materials and process of its preparation Bridgestone Corporation (JP) 1989-01-11 EP disclosed