Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGKA | P23743 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | WRN | Q14191 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | PSMB8 | P28062 | 2/20 | 0.34 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.34 |
| ▸ | NAAA | Q02083 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL141048 | 0.92 | ADRA2A (0.36) | DGKAADRA2AADRA1ABLMMAPT | |
| SCHEMBL12060996 | 0.89 | ALDH1A1 (0.41) | DGKAADRA2AADRA1ABLMMAPT | |
| SCHEMBL13540116 | 0.89 | GAA (0.41) | DGKAGAABLMALDH1A1CYP1A2 | |
| SCHEMBL409627 | 0.87 | SMN1; SMN2 (0.40) | DGKAGAAADRA2AADRA1ABLM | |
| SCHEMBL13041856 | 0.87 | ADRA2A (0.33) | DGKAADRA2AADRA1ABLMMAPT | |
| SCHEMBL126873 | 0.87 | ADRA2A (0.33) | DGKAADRA2AADRA1ABLMMAPT | |
| SCHEMBL30474637 | 0.86 | ALDH1A1 (0.38) | GAABLMALDH1A1CYP1A2HPGD | |
| SCHEMBL57077 | 0.86 | ALDH1A1 (0.38) | GAABLMALDH1A1CYP1A2HPGD | |
| SCHEMBL17756748 | 0.86 | ALDH1A1 (0.38) | GAABLMALDH1A1CYP1A2HPGD | |
| SCHEMBL18915652 | 0.86 | ALDH1A1 (0.44) | DGKAGAAMAPTALDH1A1NAAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0359996-B1 | Synthetic amino acid-and/or peptide-containing graft copolymers | AL MARZOOK UNITED COMMERCIAL C (KW) | 1994-04-13 | — | — | EP | disclosed |
| EP-0359996-A2 | Synthetic amino acid-and/or peptide-containing graft copolymers | Al Marzook United Commercial Co. (KW) | 1990-03-28 | — | — | EP | disclosed |
| US-4908404-A | Water soluble high molecular weight cationic graft polymer | BIOPOLYMERS, INC. (US) | 1990-03-13 | — | — | US | disclosed |