Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | PSMB8 | P28062 | 2/20 | 0.34 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.34 |
| ▸ | DGKA | P23743 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | PRKCA | P17252 | 3/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16214307 | 0.95 | SMN1; SMN2 (0.37) | SMN1; SMN2HPGDHTTADRA2AADRA1A | |
| SCHEMBL12420409 | 0.95 | SMN1; SMN2 (0.37) | SMN1; SMN2HPGDHTTADRA2AADRA1A | |
| SCHEMBL17563496 | 0.94 | SMN1; SMN2 (0.41) | SMN1; SMN2HPGDHTTMAPTTSHR | |
| SCHEMBL141048 | 0.92 | ADRA2A (0.36) | SMN1; SMN2ADRA2AADRA1AMAPTBLM | |
| SCHEMBL13535883 | 0.91 | SMN1; SMN2 (0.36) | SMN1; SMN2HPGDHTTMAPTTSHR | |
| SCHEMBL13535837 | 0.90 | HPGD (0.37) | SMN1; SMN2HPGDHTTADRA2AADRA1A | |
| SCHEMBL12285234 | 0.90 | SMN1; SMN2 (0.39) | SMN1; SMN2HPGDHTTMAPTTSHR | |
| 2-Methoxyethanol SCHEMBL29386411 | 0.89 | HPGD (0.35) | SMN1; SMN2HPGDHTTADRA2AADRA1A | |
| SCHEMBL24564946 | 0.87 | SMN1; SMN2 (0.40) | SMN1; SMN2HPGDHTTMAPTTSHR | |
| SCHEMBL9329901 | 0.87 | DGKA (0.37) | HPGDADRA2AADRA1AMAPTBLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120064061-A1 | ADHESIVE COMPOSITION COMPRISING TANNIN, POLY(ETHYLENE GLYCOL), AND WATER, LOWER ALCOHOL OR MIXTURE THEREOF | INNOTHERAPY INC. (KR) | 2012-03-15 | — | — | US | disclosed |
| US-20110098344-A1 | DRUG CARRIER | NIPPON SHINYAKU CO., LTD. (JP) | 2011-04-28 | — | — | US | disclosed |
| US-20100160556-A1 | GLP-1 Fusion Peptides Conjugated to Polymer(s), Their Production and Use | BIOCOMPATIBLES UK LTD. (GB) | 2010-06-24 | — | — | US | disclosed |
| US-20100009908-A1 | Galectin 9-Polymer Conjugates | GALPHARMA CO., LTD. (JP) | 2010-01-14 | — | — | US | disclosed |
| US-7320791-B2 | Monoclonal antibody for analysis and clearance of polyethylene glycol and polyethylene glycol-modified molecules | ACADEMIA SINICA (TW) | 2008-01-22 | — | — | US | disclosed |
| US-20040014156-A1 | Monoclonal antibody for analysis and clearance of polyethylene glycol and polyethylene glycol-modified molecules | ACADEMIA SINICA | 2004-01-22 | — | — | US | disclosed |
| US-6596849-B1 | Monoclonal antibody for use in the treatment of cell proliferative disorders | ACADEMIA SINICA (TW) | 2003-07-22 | — | — | US | disclosed |
| US-20010028881-A1 | Monoclonal antibody for analysis and clearance of polyethylene glycol and polyethylene glycol-modified molecules | ACADEMIA SINICA | 2001-10-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120064061-A1 | ADHESIVE COMPOSITION COMPRISING TANNIN, POLY(ETHYLENE GLYCOL), AND WATER, LOWER ALCOHOL OR MIXTURE THEREOF | EPCAM, ICAM1, VCAM1 | SMN1; SMN2 3523/4885HPGD 920/4885HTT 1311/4885 |
| US-20100160556-A1 | GLP-1 Fusion Peptides Conjugated to Polymer(s), Their Production and Use | IAPP, GIPR, GLP1R | SMN1; SMN2 399/4885HPGD 4246/4885HTT 615/4885 |
| US-20110098344-A1 | DRUG CARRIER | SLC10A1, NPC1L1, SGMS1 | SMN1; SMN2 2962/4885HPGD 1682/4885HTT 3695/4885 |
| US-20100009908-A1 | Galectin 9-Polymer Conjugates | LGALS9, LGALS1, LGALS2 | SMN1; SMN2 3323/4885HPGD 1550/4885HTT 1297/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.