Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28184322 | 0.86 | TSHR (0.37) | TSHRALDH1A1THRB | |
| SCHEMBL933010 | 0.82 | TSHR (0.37) | TSHRALDH1A1THRB | |
| SCHEMBL11044650 | 0.80 | TSHR (0.33) | TSHRALDH1A1THRB | |
| SCHEMBL7866733 | 0.76 | TSHR (0.36) | TSHRALDH1A1THRB | |
| SCHEMBL7866736 | 0.76 | THRB (0.49) | TSHRALDH1A1THRB | |
| SCHEMBL1719176 | 0.75 | TSHR (0.37) | TSHRALDH1A1THRB | |
| SCHEMBL10889597 | 0.74 | TSHR (0.37) | TSHRALDH1A1 | |
| SCHEMBL524563 | 0.73 | TSHR (0.38) | TSHRALDH1A1THRB | |
| SCHEMBL3446566 | 0.72 | TSHR (0.52) | TSHRALDH1A1THRB | |
| SCHEMBL17541578 | 0.72 | ALDH1A1 (0.38) | TSHRALDH1A1THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9039174-B2 | Ethylenically unsaturated polymerizable groups comprising polycarbosiloxane monomers | BAUSCH & LOMB INCORPORATED (US) | 2015-05-26 | — | — | US | disclosed |
| EP-2452212-B1 | MONO ETHYLENICALLY UNSATURATED POLYMERIZABLE GROUP CONTAINING POLYCARBOSILOXANE MONOMERS | BAUSCH & LOMB (US) | 2015-03-25 | — | — | EP | disclosed |
| WO-2014143926-A1 | ETHYLENICALLY UNSATURATED POLYMERIZABLE GROUPS COMPRISING POLYCARBOSILOXANE MONOMERS | BAUSCH & LOMB INCORPORATED (US) | 2014-09-18 | — | — | WO | disclosed |
| US-8827447-B2 | Mono ethylenically unsaturated polymerizable group containing polycarbosiloxane monomers | BAUSCH & LOMB INCORPORATED (US) | 2014-09-09 | — | — | US | disclosed |
| US-20130289294-A1 | ETHYLENICALLY UNSATURATED POLYMERIZABLE GROUPS COMPRISING POLYCARBOSILOXANE MONOMERS | BAUSCH HEALTH AMERICAS, INC. | 2013-10-31 | — | — | US | disclosed |
| US-20130197125-A1 | MONO ETHYLENICALLY UNSATURATED POLYMERIZABLE GROUP CONTAINING POLYCARBOSILOXANE MONOMERS | BAUSCH & LOMB INCORPORATED (US) | 2013-08-01 | — | — | US | disclosed |
| US-8420711-B2 | Mono ethylenically unsaturated polymerizable group containing polycarbosiloxane monomers | BAUSCH & LOMB INCORPORATED (US) | 2013-04-16 | — | — | US | disclosed |
| EP-2452212-A2 | MONO ETHYLENICALLY UNSATURATED POLYMERIZABLE GROUP CONTAINING POLYCARBOSILOXANE MONOMERS | Bausch & Lomb Incorporated (US) | 2012-05-16 | — | — | EP | disclosed |
| US-7994356-B2 | Mono ethylenically unsaturated polycarbosiloxane monomers | BAUSCH & LOMB INCORPORATED (US) | 2011-08-09 | — | — | US | disclosed |
| US-7915323-B2 | Mono ethylenically unsaturated polycarbosiloxane monomers | BAUSCH & LAMB INCORPORATED (US) | 2011-03-29 | — | — | US | disclosed |
| US-20110009587-A1 | MONO ETHYLENICALLY UNSATURATED POLYCARBOSILOXANE MONOMERS | ORAPHARMA, INC. | 2011-01-13 | — | — | US | disclosed |
| US-20110009658-A1 | Mono Ethylenically Unsaturated Polycarbosiloxane Monomers | BAUSCH HEALTH AMERICAS, INC. | 2011-01-13 | — | — | US | disclosed |
| US-20110009519-A1 | MONO ETHYLENICALLY UNSATURATED POLYMERIZABLE GROUP CONTAINING POLYCARBOSILOXANE MONOMERS | SOLTA MEDICAL, INC. | 2011-01-13 | — | — | US | disclosed |
| WO-2011005937-A2 | MONO ETHYLENICALLY UNSATURATED POLYMERIZABLE GROUP CONTAINING POLYCARBOSILOXANE MONOMERS | BAUSCH & LOMB INCORPORATED (US) | 2011-01-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110009658-A1 | Mono Ethylenically Unsaturated Polycarbosiloxane Monomers | ALOX5, ALOX12, ELOVL5 | TSHR 4814/4885ALDH1A1 845/4885THRB 4789/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.