Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM3 | P20309 | 9/20 | 0.46 |
| ▸ | BCHE | P06276 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | TMEM97 | Q5BJF2 | 7/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9333430 | 0.85 | CHRM3 (0.38) | CHRM3BCHEGAAEPHX1 | |
| SCHEMBL9333382 | 0.82 | MEN1 (0.36) | BCHETMEM97EPHX1 | |
| SCHEMBL9333184 | 0.81 | CHRM3 (0.55) | CHRM3GAAEPHX1 | |
| SCHEMBL9330460 | 0.81 | GAA (0.40) | CHRM3BCHEGAATMEM97EPHX1 | |
| Fumaric Acid SCHEMBL9345013 | 0.78 | GNAI3 (0.48) | GAA | |
| SCHEMBL9333237 | 0.76 | SMN1; SMN2 (0.47) | EPHX1 | |
| SCHEMBL9329947 | 0.72 | MEN1 (0.35) | CHRM3BCHETMEM97EPHX1 | |
| SCHEMBL9330841 | 0.72 | SMN1; SMN2 (0.48) | BCHEGAAEPHX1 | |
| SCHEMBL14607630 | 0.72 | GNAI3 (0.38) | — | |
| SCHEMBL27411942 | 0.70 | CHRM3 (0.50) | CHRM3EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0366004-B1 | Cyclic azaaliphatic compounds with a nitroxy group, process for their preparation and pharmaceutical compositions thereof | BOEHRINGER MANNHEIM GMBH (DE) | 1994-03-30 | — | — | EP | disclosed |
| EP-0366004-A1 | Cyclic azaaliphatic compounds with a nitroxy group, process for their preparation and pharmaceutical compositions thereof | Roche Diagnostics GmbH (DE) | 1990-05-02 | — | — | EP | disclosed |