Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.34 |
| ▸ | BCHE | P06276 | 4/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | TMEM97 | Q5BJF2 | 6/20 | 0.33 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9333430 | 0.84 | CHRM3 (0.38) | MEN1KMT2AEPHX1BCHEALDH1A1 | |
| SCHEMBL9330164 | 0.82 | CHRM3 (0.46) | EPHX1BCHETMEM97 | |
| SCHEMBL9332538 | 0.81 | CYP2D6 (0.40) | MEN1KMT2ACYP2D6MAOBEPHX1 | |
| Fumaric Acid SCHEMBL9345070 | 0.77 | ALDH1A1 (0.44) | MEN1KMT2AKDM4EALDH1A1TDP1 | |
| SCHEMBL9330460 | 0.77 | GAA (0.40) | MEN1KMT2AEPHX1BCHEALDH1A1 | |
| SCHEMBL9333237 | 0.75 | SMN1; SMN2 (0.47) | MEN1KMT2ACYP2D6EPHX1ALDH1A1 | |
| SCHEMBL9329947 | 0.71 | MEN1 (0.35) | MEN1KMT2AEPHX1BCHEALDH1A1 | |
| SCHEMBL9330841 | 0.68 | SMN1; SMN2 (0.48) | MEN1KMT2ACYP2D6EPHX1BCHE | |
| SCHEMBL2417145 | 0.68 | MEN1 (0.44) | MEN1KMT2AEPHX1BCHECYP2C9 | |
| SCHEMBL9330344 | 0.68 | MEN1 (0.36) | MEN1KMT2AEPHX1BCHECYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0366004-B1 | Cyclic azaaliphatic compounds with a nitroxy group, process for their preparation and pharmaceutical compositions thereof | BOEHRINGER MANNHEIM GMBH (DE) | 1994-03-30 | — | — | EP | disclosed |