Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
| ▸ | MMP9 | P14780 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 5/20 | 0.41 |
| ▸ | NCF1 | P14598 | 1/20 | 0.39 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.35 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.35 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
| ▸ | NOS3 | P29474 | 1/20 | 0.30 |
| ▸ | NOS1 | P29475 | 1/20 | 0.30 |
| ▸ | NOS2 | P35228 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fumaric Acid SCHEMBL9348961 | 0.88 | MMP2 (0.38) | MMP2MMP9ACHENCF1GNAI3 | |
| SCHEMBL9345631 | 0.85 | MMP2 (0.34) | MMP2MMP9ACHEGNAI3GNAO1 | |
| SCHEMBL9332559 | 0.80 | PRMT3 (0.39) | MMP2MMP9ACHEGNAI3GNAO1 | |
| SCHEMBL9345623 | 0.80 | GABRP (0.38) | MMP2MMP9GNAI3GNAO1GNAI1 | |
| SCHEMBL8957457 | 0.77 | MMP2 (0.39) | MMP2MMP9ALDH1A1 | |
| SCHEMBL2803178 | 0.77 | MMP2 (0.38) | MMP2MMP9ALDH1A1 | |
| SCHEMBL9330359 | 0.77 | MMP2 (0.38) | MMP2MMP9ALDH1A1 | |
| SCHEMBL14394506 | 0.76 | GNAI3 (0.46) | GNAI3GNAO1GNAI1ALDH1A1 | |
| SCHEMBL7822303 | 0.74 | MMP2 (0.38) | MMP2MMP9ALDH1A1 | |
| SCHEMBL8259490 | 0.74 | MMP2 (0.38) | MMP2MMP9HRH3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0366004-B1 | Cyclic azaaliphatic compounds with a nitroxy group, process for their preparation and pharmaceutical compositions thereof | BOEHRINGER MANNHEIM GMBH (DE) | 1994-03-30 | — | — | EP | disclosed |
| EP-0366004-A1 | Cyclic azaaliphatic compounds with a nitroxy group, process for their preparation and pharmaceutical compositions thereof | Roche Diagnostics GmbH (DE) | 1990-05-02 | — | — | EP | disclosed |