Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | GFER | P55789 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.44 |
| ▸ | FABP7 | O15540 | 1/20 | 0.42 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6611364 | 0.93 | KMT2A (0.50) | KMT2AMEN1HTTGFERHSD17B10 | |
| SCHEMBL697595 | 0.88 | KMT2A (0.60) | KMT2AMEN1HTTGFERHSD17B10 | |
| SCHEMBL1927968 | 0.83 | LMNA (0.59) | KMT2AMEN1HTTGFERHSD17B10 | |
| SCHEMBL10490891 | 0.83 | KMT2A (0.50) | KMT2AMEN1HTTGFERHSD17B10 | |
| SCHEMBL10596156 | 0.81 | KMT2A (0.55) | KMT2AMEN1HTTGFERHSD17B10 | |
| SCHEMBL9328838 | 0.80 | KMT2A (0.65) | KMT2AMEN1HTTGFERHSD17B10 | |
| SCHEMBL17473134 | 0.80 | KMT2A (0.54) | KMT2AMEN1HTTGFERHSD17B10 | |
| SCHEMBL5654161 | 0.80 | RAB9A (0.56) | KMT2AMEN1HTTGFERHSD17B10 | |
| SCHEMBL9573616 | 0.80 | ALDH1A1 (0.62) | KMT2AMEN1HTTGFERHSD17B10 | |
| SCHEMBL8942876 | 0.80 | TDP1 (0.44) | KMT2AMEN1HSD17B10ALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5294737-A | Hydrolysis, cyclization, condensation | THE RESEARCH FOUNDATION STATE UNIVERSITY OF NEW YORK (US) | 1994-03-15 | — | — | US | claimed |
| US-4684641-A | BACTERICIDES | PFIZER INC. (US) | 1987-08-04 | — | — | US | claimed |
| EP-0219926-A2 | Cephalosporins, processes for their preparation and pharmaceutical compositions containing them | BEECHAM GROUP PLC (GB) | 1987-04-29 | — | — | EP | claimed |
| EP-0168177-A2 | Cephalosporin antibiotics | Pfizer Limited (GB) | 1986-01-15 | — | — | EP | claimed |
| US-4430344-A | Antihypertensive 4-thiazolidinecarboxylic acids | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1984-02-07 | — | — | US | claimed |
| US-4347371-A | HYPERTENSIVE AGENTS; ANTIDIABETIC AGENTS; VISION DEFECTS | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1982-08-31 | — | — | US | claimed |
| EP-0031104-A1 | Thiazolidine compounds, processes for their preparation and pharmaceutical compositions containing them | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1981-07-01 | — | — | EP | claimed |
| US-4181800-A | ANTIBIOTICS FROM SUBSTITUTED PERHYDRO-S-TRIAZINES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1980-01-01 | — | — | US | claimed |
| US-5359017-A | Using an organoiron compound | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 1994-10-25 | — | — | US | disclosed |
| EP-0511405-A1 | CATIONICALLY POLYMERIZABLE ORGANIC MATERIAL COMPOSITION AND STABILIZATION OF SAID COMPOSITION | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 1992-11-04 | — | — | EP | disclosed |
| US-4835150-A | ANTIBIOTICS | BEECHAM GROUP P.L.C. (GB) | 1989-05-30 | — | — | US | disclosed |
| EP-0308559-A2 | Cephalosporins, process for their preparation, pharmaceutical compositions containing them and intermediates | BEECHAM GROUP PLC (GB) | 1989-03-29 | — | — | EP | disclosed |
| EP-0265185-A2 | Cephalosporins, processes for their preparation and pharmaceutical compositions containing them | BEECHAM GROUP PLC (GB) | 1988-04-27 | — | — | EP | disclosed |
| US-4684641-A | BACTERICIDES | PFIZER INC. (US) | 1987-08-04 | — | — | US | disclosed |
| US-4410542-A | HYPOTENSIVE AGENTS, PYRROLINE-1,2-DICARBOXYLIC ACID DERIVATIVES | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1983-10-18 | — | — | US | disclosed |
| EP-0067612-A1 | Penicillin derivatives | BEECHAM GROUP PLC (GB) | 1982-12-22 | — | — | EP | disclosed |
| US-4347371-A | HYPERTENSIVE AGENTS; ANTIDIABETIC AGENTS; VISION DEFECTS | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1982-08-31 | — | — | US | disclosed |
| US-4288364-A | REACTING A 3-/2-HYDROXYIMINOACETYLAMINO/-2-OXOAZETIDINE WITH AN ORGANIC CARBONATE OR ACYL HALIDE | CIBA-GEIGY CORPORATION (US) | 1981-09-08 | — | — | US | disclosed |
| US-4203982-A | Arylmalonamidomethoxycephalosporins | SHIONOGI & CO., LTD. (JP) | 1980-05-20 | — | — | US | disclosed |
| EP-0005507-A1 | Process for the fragmentation of 3-(2-hydroxyimino-acetylamino)-2-oxo azetidin compounds and compounds obtained thereby | CIBA-GEIGY AG (CH) | 1979-11-28 | — | — | EP | disclosed |