Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 5/20 | 0.52 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.52 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.46 |
| ▸ | TERT | O14746 | 3/20 | 0.45 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.45 |
| ▸ | PPARG | P37231 | 3/20 | 0.45 |
| ▸ | PPARD | Q03181 | 3/20 | 0.45 |
| ▸ | PPARA | Q07869 | 3/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.45 |
| ▸ | BLM | P54132 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | FABP4 | P15090 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | GMNN | O75496 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21423390 | 1.00 | FAAH (0.52) | FAAHTRPV1KCNH2EPHX2TERT | |
| SCHEMBL19032626 | 1.00 | FAAH (0.52) | FAAHTRPV1KCNH2EPHX2TERT | |
| SCHEMBL11757316 | 1.00 | FAAH (0.52) | FAAHTRPV1KCNH2EPHX2TERT | |
| SCHEMBL8853677 | 1.00 | FAAH (0.52) | FAAHTRPV1KCNH2EPHX2TERT | |
| SCHEMBL8853696 | 1.00 | FAAH (0.52) | FAAHTRPV1KCNH2EPHX2TERT | |
| SCHEMBL25498084 | 0.98 | FAAH (0.50) | FAAHTRPV1KCNH2EPHX2TERT | |
| SCHEMBL5488036 | 0.95 | FAAH (0.52) | FAAHTRPV1KCNH2EPHX2TERT | |
| SCHEMBL3272411 | 0.95 | FAAH (0.52) | FAAHTRPV1KCNH2EPHX2TERT | |
| SCHEMBL3920135 | 0.95 | FAAH (0.52) | FAAHTRPV1KCNH2EPHX2TERT | |
| Water SCHEMBL4537161 | 0.93 | FAAH (0.50) | FAAHTRPV1KCNH2EPHX2TERT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10881730-B2 | Immunomodulatory therapeutic MRNA compositions encoding activating oncogene mutation peptides | MODERNATX, INC. (US) | 2021-01-05 | — | — | US | disclosed |
| US-20200131498-A1 | POLYNUCLEOTIDES ENCODING METHYLMALONYL-COA MUTASE | MODERNATX, INC. | 2020-04-30 | — | — | US | disclosed |
| US-20190275170-A1 | POLYNUCLEOTIDES ENCODING JAGGED1 FOR THE TREATMENT OF ALAGILLE SYNDROME | MODERNATX, INC. (US) | 2019-09-12 | — | — | US | disclosed |
| US-20190175727-A1 | IMMUNOMODULATORY THERAPEUTIC MRNA COMPOSITIONS ENCODING ACTIVATING ONCOGENE MUTATION PEPTIDES | ARES CAPITAL CORPORATION, AS AGENT | 2019-06-13 | — | — | US | disclosed |
| US-5362910-A | Germicidal and fungicidal agent and a germicidal and fungicidal method | NICCA CHEMICAL CO., LTD. (JP) | 1994-11-08 | — | — | US | disclosed |
| EP-0537426-A1 | A germicidal and fungicidal agent and a germicidal and fungicidal method | NICCA CHEMICAL CO., LTD. (JP) | 1993-04-21 | — | — | EP | disclosed |
| US-4048118-A | ALKALI METAL SALT OF ORGANIC ACID, AMINE SALT OF PHYTIC ACID | SHOWA DENKO K.K. (JA) | 1977-09-13 | — | — | US | disclosed |
| US-3956252-A | BASIC NITROGEN-CONTAINING SALT OF PHYTIC ACID | SHOWA DENKU K.K. (JA) | 1976-05-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10881730-B2 | Immunomodulatory therapeutic MRNA compositions encoding activating oncogene mutation peptides | TP53, MYC, KRAS | FAAH 4718/4885TRPV1 2754/4885KCNH2 4428/4885 |
| US-20190175727-A1 | IMMUNOMODULATORY THERAPEUTIC MRNA COMPOSITIONS ENCODING ACTIVATING ONCOGENE MUTATION PEPTIDES | TP53, MYC, KRAS | FAAH 4718/4885TRPV1 2754/4885KCNH2 4428/4885 |
| US-20200131498-A1 | POLYNUCLEOTIDES ENCODING METHYLMALONYL-COA MUTASE | POLM, MCM6, MCM3 | FAAH 3913/4885TRPV1 4873/4885KCNH2 4165/4885 |
| US-20190275170-A1 | POLYNUCLEOTIDES ENCODING JAGGED1 FOR THE TREATMENT OF ALAGILLE SYNDROME | AARS1, IARS1, NOTCH1 | FAAH 2004/4885TRPV1 3359/4885KCNH2 4296/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.