SCHEMBL14927366

SCHEMBL14927366

O=COc1ccccc1-c1ccccc1C(=O)O

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 8/20 0.47
HSD17B10 Q99714 6/20 0.47
HPGD P15428 5/20 0.47
MAPT P10636 1/20 0.47
CYP2C9 P11712 2/20 0.46
CYP3A4 P08684 1/20 0.46
ALOX12 P18054 1/20 0.46
LMNA P02545 2/20 0.45
POLB P06746 1/20 0.45
ALDH1A1 P00352 6/20 0.45
ALOX15 P16050 1/20 0.45
ESR1 P03372 1/20 0.44
ITGB3 P05106 1/20 0.44
ITGA2B P08514 1/20 0.44
HMGB1 P09429 1/20 0.44
TSHR P16473 1/20 0.44
GGT1 P19440 1/20 0.44
PTGS1 P23219 1/20 0.44
PTGS2 P35354 1/20 0.44
BLM P54132 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL933092 0.85 KDM4E (0.58) KDM4EHSD17B10HPGDMAPTCYP2C9
Cyclohexane SCHEMBL11130138 0.80 KDM4E (0.53) KDM4EHSD17B10HPGDMAPTCYP2C9
SCHEMBL17718224 0.79 ALDH1A1 (0.50) KDM4EHSD17B10HPGDMAPTCYP2C9
SCHEMBL36145 0.78 ALDH1A1 (0.72) KDM4EHSD17B10HPGDMAPTCYP2C9
SCHEMBL30028907 0.78 ALDH1A1 (0.72) KDM4EHSD17B10HPGDMAPTCYP2C9
SCHEMBL6257888 0.78 KDM4E (0.52) KDM4EHSD17B10HPGDMAPTCYP2C9
SCHEMBL536179 0.78 HTT (0.62) KDM4EHSD17B10HPGDALDH1A1ESR1
1,2-Dichlorobenzene SCHEMBL28253435 0.77 ALDH1A1 (0.55) KDM4EHSD17B10HPGDMAPTCYP2C9
SCHEMBL14944734 0.76 CA12 (0.46) KDM4EHSD17B10HPGDMAPTCYP2C9
SCHEMBL9634001 0.76 HTT (0.61) KDM4EHSD17B10HPGDALDH1A1ESR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12037304-B2 Monomer and polymer, compensation film, optical film, and display device SAMSUNG ELECTRONICS CO., LTD. (KR) 2024-07-16 US disclosed
US-9862658-B2 Use of polymers as heterogeneous hydrogen donors for hydrogenation reactions INSTITUTO MEXICANO DEL PETROLEO (MX) 2018-01-09 US disclosed
US-20170292022-A1 Sulfone polymer composition SOLVAY SPECIALTY POLYMERS USA, LLC (US) 2017-10-12 US disclosed
US-20170121594-A1 Proppant particulates and methods of using such particulates in subterranean applications SOLVAY SPECIALTY POLYMERS USA (US) 2017-05-04 US disclosed
US-20170062826-A1 ADHESIVE COMPOSITION, ELECTRODE COMPOSITION, ELECTRODE AND LITHIUM BATTERY NATIONAL TAIWAN UNIVERSITY OF SCIENCE AND TECHNOLOGY (TW) 2017-03-02 US disclosed
US-20160200644-A1 Use of polymers as heterogeneous hydrogen donors for hydrogenation reactions INSTITUTO MEXICANO DEL PETRÓLEO (MX) 2016-07-14 US disclosed
US-20150255730-A1 BIPHENYL DERIVATIVE AND ORGANIC ELECTROLUMINESCENT DEVICE INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 2015-09-10 US disclosed
US-20140213538-A1 LYSOPHOSPHATIDIC ACID RECEPTOR ANTAGONISTS INTERMUNE, INC. 2014-07-31 US disclosed
US-20130112409-A1 Proppant particulates and methods of using such particulates in subterranean applications SOLVAY SPECIALTY POLYMERS USA, LLC (US) 2013-05-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140213538-A1 LYSOPHOSPHATIDIC ACID RECEPTOR ANTAGONISTS LPAR1, LPAR2, LPAR5 KDM4E 4418/4885HSD17B10 2376/4885HPGD 1026/4885
US-20160200644-A1 Use of polymers as heterogeneous hydrogen donors for hydrogenation reactions HNMT, PARG, NUDT1 KDM4E 4638/4885HSD17B10 834/4885HPGD 11/4885
US-20150255730-A1 BIPHENYL DERIVATIVE AND ORGANIC ELECTROLUMINESCENT DEVICE NPY5R, AFF1, KCNA5 KDM4E 2282/4885HSD17B10 731/4885HPGD 3285/4885
US-12037304-B2 Monomer and polymer, compensation film, optical film, and display device PYM1, RAD51, CRY1 KDM4E 3155/4885HSD17B10 4593/4885HPGD 4316/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.