Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | PLA2G7 | Q13093 | 3/20 | 0.34 |
| ▸ | NPBWR1 | P48145 | 2/20 | 0.34 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.34 |
| ▸ | CDK4 | P11802 | 1/20 | 0.32 |
| ▸ | CCND1 | P24385 | 1/20 | 0.32 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.32 |
| ▸ | KDR | P35968 | 1/20 | 0.32 |
| ▸ | TEK | Q02763 | 1/20 | 0.32 |
| ▸ | PDE2A | O00408 | 2/20 | 0.32 |
| ▸ | CBFB | Q13951 | 1/20 | 0.32 |
| ▸ | RAF1 | P04049 | 1/20 | 0.31 |
| ▸ | BRAF | P15056 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9331777 | 0.91 | MAPT (0.45) | MAPTHPGDKDM4EPOLBGAA | |
| SCHEMBL9335269 | 0.87 | NPSR1 (0.40) | MAPTHPGDKDM4EPOLBHSD17B10 | |
| SCHEMBL9332308 | 0.84 | PSMB8 (0.40) | NPBWR1MCHR1KDRTEKCBFB | |
| SCHEMBL11818482 | 0.80 | MAPT (0.46) | MAPTHPGDKDM4EPOLBGAA | |
| SCHEMBL8692479 | 0.79 | NPBWR1 (0.33) | HPGDNPBWR1MCHR1TLR7 | |
| SCHEMBL9335261 | 0.78 | KDM4E (0.44) | MAPTHPGDKDM4EPOLBHSD17B10 | |
| SCHEMBL4493478 | 0.76 | NPBWR1 (0.46) | MAPTPOLBNPBWR1MCHR1TLR7 | |
| SCHEMBL9332317 | 0.76 | PSMB8 (0.48) | KDRTEKRAF1BRAF | |
| SCHEMBL9332491 | 0.74 | METAP2 (0.51) | MAPTKDM4ENPBWR1MCHR1 | |
| SCHEMBL8825678 | 0.74 | NPBWR1 (0.33) | HPGDNPBWR1MCHR1TLR7KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0448206-B1 | Substituted benzimidazole and indazole derivatives, processes for their preparation and their use as herbicides | ZENECA LTD (GB) | 1994-12-28 | — | — | EP | disclosed |
| US-5306692-A | Herbicidal indazole and benzimidazole compounds | ZENECA LIMITED (GB) | 1994-04-26 | — | — | US | disclosed |
| EP-0448206-A2 | Substituted benzimidazole and indazole derivatives, processes for their preparation and their use as herbicides | ZENECA LIMITED (GB) | 1991-09-25 | — | — | EP | disclosed |