Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | KDR | P35968 | 6/20 | 0.39 |
| ▸ | TEK | Q02763 | 5/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | RAF1 | P04049 | 1/20 | 0.36 |
| ▸ | CHEK2 | O96017 | 5/20 | 0.36 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9335269 | 0.91 | NPSR1 (0.40) | KDM4EALDH1A1HPGDMAPTCYP1A2 | |
| SCHEMBL9331777 | 0.87 | MAPT (0.45) | KDM4EALDH1A1HPGDMAPTHSD17B10 | |
| SCHEMBL9332317 | 0.85 | PSMB8 (0.48) | KDRTEKRAF1CHEK2 | |
| SCHEMBL8825678 | 0.80 | NPBWR1 (0.33) | HPGDLMNAHTTKDRTEK | |
| SCHEMBL27348469 | 0.79 | RAB9A (0.33) | KDRTEKNPBWR1 | |
| SCHEMBL9331787 | 0.78 | MAPT (0.39) | KDM4EALDH1A1HPGDMAPTHSD17B10 | |
| SCHEMBL9332491 | 0.78 | METAP2 (0.51) | KDM4EMAPTCYP1A2HTTNPBWR1 | |
| SCHEMBL9335298 | 0.77 | KMT2A (0.41) | ALDH1A1HPGDHTTKDRTEK | |
| SCHEMBL9332308 | 0.76 | PSMB8 (0.40) | KDRTEKRAF1NPBWR1 | |
| SCHEMBL8692479 | 0.75 | NPBWR1 (0.33) | HPGDLMNAHTTNPBWR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0448206-B1 | Substituted benzimidazole and indazole derivatives, processes for their preparation and their use as herbicides | ZENECA LTD (GB) | 1994-12-28 | — | — | EP | disclosed |
| US-5306692-A | Herbicidal indazole and benzimidazole compounds | ZENECA LIMITED (GB) | 1994-04-26 | — | — | US | disclosed |
| EP-0448206-A2 | Substituted benzimidazole and indazole derivatives, processes for their preparation and their use as herbicides | ZENECA LIMITED (GB) | 1991-09-25 | — | — | EP | disclosed |