SCHEMBL93320

SCHEMBL93320

O=C=Nc1ccc(I)cc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 3/20 0.56
TSHR P16473 1/20 0.56
MAPK1 P28482 1/20 0.52
TDP1 Q9NUW8 1/20 0.52
TRPA1 O75762 1/20 0.43
SLC22A2 O15244 1/20 0.41
SLC22A1 O15245 1/20 0.41
SLC22A3 O75751 1/20 0.41
CYP1A2 P05177 1/20 0.40
TPMT P51580 1/20 0.33
SIGMAR1 Q99720 1/20 0.33
GABRA1 P14867 1/20 0.32
GABRB2 P47870 1/20 0.32
CA1 P00915 3/20 0.32
CA2 P00918 3/20 0.32
F2 P00734 1/20 0.30
PRSS1 P07477 1/20 0.30
PRSS2 P07478 1/20 0.30
PRSS3 P35030 1/20 0.30
FAAH O00519 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Cyanate SCHEMBL9443076 0.89 CYP3A4 (0.47) CYP3A4TSHRMAPK1TDP1TRPA1
SCHEMBL17751129 0.87 CYP3A4 (0.80) CYP3A4TSHRMAPK1TDP1TRPA1
SCHEMBL15430 0.86 CYP3A4 (0.70) CYP3A4TSHRMAPK1TDP1TRPA1
SCHEMBL27741428 0.83 CYP3A4 (0.67) CYP3A4TSHRMAPK1TDP1TRPA1
Water SCHEMBL28889229 0.83 CYP3A4 (0.67) CYP3A4TSHRMAPK1TDP1TRPA1
Ammonia Solution, Strong SCHEMBL28239770 0.83 CYP3A4 (0.67) CYP3A4TSHRMAPK1TDP1TRPA1
SCHEMBL8700318 0.81 LTA4H (0.41) CYP3A4TSHRMAPK1TDP1CA1
SCHEMBL9443311 0.78 LMNA (0.41) CYP3A4TSHRMAPK1TDP1TRPA1
SCHEMBL23721668 0.78 CYP3A4 (0.61) CYP3A4TSHRMAPK1TDP1TRPA1
SCHEMBL333218 0.78 CYP3A4 (0.61) CYP3A4TSHRMAPK1TDP1TRPA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 365 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111100732-B Soap urethane lubricating grease and preparation method thereof 中国石油化工股份有限公司 2022-10-21 CN claimed
CN-113522048-B Oil-water separation membrane based on oxime carbamate bond, preparation method and application thereof 陕西科技大学 2022-07-01 CN claimed
CN-110483572-B Trinuclear gold alkynyl urea complex with tetrahedral oxyanion recognition function and preparation method thereof 广州钰芯传感科技有限公司 2022-04-12 CN claimed
CN-114005680-A Cellulose gel electrolyte capable of being cured in situ and application thereof 北京石油化工学院 2022-02-01 CN claimed
CN-113522048-A Oil-water separation membrane based on oxime carbamate bond, preparation method and application thereof 陕西科技大学 2021-10-22 CN claimed
CN-111100732-A Soap urethane lubricating grease and preparation method thereof 中国石油化工股份有限公司 2020-05-05 CN claimed
US-20090216006-A1 COVALENTLY BOUND POLYSACCHARIDE-BASED CHIRAL STATIONARY PHASES AND METHOD FOR THEIR PREPARATION XU HUI 2009-08-27 US claimed
EP-1377589-B1 OXAZOLYL-PYRAZOLE DERIVATIVES AS KINASE INHIBITORS PHARMACIA ITALIA SPA (IT) 2005-09-07 EP claimed
EP-4713378-A1 ESTERIFIED ETHANOLAMINES FOR PREPARING ISOCYANURATE POLYMERS Covestro Deutschland AG (DE) 2026-03-25 EP disclosed
US-12577373-B2 Carbodiimide composition, curing agent composition, coating composition and resin cured product ASAHI KASEI KABUSHIKI KAISHA (JP) 2026-03-17 US disclosed
EP-4688743-A1 INHIBITORS OF SPINSTER HOMOLOG 2 (SPNS2) FOR USE IN THERAPY University of Virginia Patent Foundation (US) 2026-02-11 EP disclosed
US-12534429-B2 Heterodimers of glutamic acid MOLECULAR INSIGHT PHARMACEUTICALS, INC. (US) 2026-01-27 US disclosed
US-20260001914-A1 MACROCYCLIC PEPTIDES TARGETING KRAS MERCK SHARP & DOHME LLC (US) 2026-01-01 US disclosed
EP-4638427-A1 AMIDINOUREA DERIVATIVES AND THEIR USE IN THE TREATMENT OF CANCER Université Côte d'Azur (FR) 2025-10-29 EP disclosed
EP-0153127-A2 N-aryl-3-aryl-4,5-dihydro-1H-pyrazole-1-carboxamides, processes for their production, insecticidal compositions containing them and methods for combatting insects ROHM AND HAAS COMPANY (US) 1985-08-28 EP disclosed
US-4163112-A INSECTICIDES VELSICOL CHEMICAL CORPORATION (US) 1979-07-31 US disclosed
US-4088766-A PRODUCTION OF PROSTAGLANDINS IN MAMMALS THE UPJOHN COMPANY (US) 1978-05-09 US disclosed
US-4053298-A HERBICIDAL COMPOSITIONS CONTAINING 1-THIADIAZOLYL-6-CARBAMOYLOXYTETRAHYDROPYRIMIDINONES AND METHODS THEREFOR VELSICOL CHEMICAL CORPORATION (US) 1977-10-11 US disclosed
US-4001256-A PROSTAGLANDIN PRODUCTION IN MAMMALS THE UPJOHN COMPANY (US) 1977-01-04 US disclosed
US-3951976-A 1-Thiadiazoly-6-carbamoyloxytetrahydropyrimidinones VELSICOL CHEMICAL CORPORATION (US) 1976-04-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12577373-B2 Carbodiimide composition, curing agent composition, coating composition and resin cured product CD38, PARP9, MCCC2 CYP3A4 2090/4885TSHR 4705/4885MAPK1 3018/4885
US-12534429-B2 Heterodimers of glutamic acid FOLH1, GLUL, SLC25A13 CYP3A4 3612/4885TSHR 790/4885MAPK1 3908/4885
US-20260001914-A1 MACROCYCLIC PEPTIDES TARGETING KRAS KRAS, NRAS, HRAS CYP3A4 4761/4885TSHR 1853/4885MAPK1 470/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.