Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | LGALS3 | P17931 | 1/20 | 0.42 |
| ▸ | P4HB | P07237 | 1/20 | 0.41 |
| ▸ | PDIA4 | P13667 | 1/20 | 0.41 |
| ▸ | PDIA3 | P30101 | 1/20 | 0.41 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.41 |
| ▸ | PRKCA | P17252 | 1/20 | 0.40 |
| ▸ | AKT1 | P31749 | 1/20 | 0.40 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24804649 | 0.92 | LMNA (0.52) | LMNAPOLBKMT2ATSHRCYP2D6 | |
| SCHEMBL9332856 | 0.92 | LMNA (0.52) | LMNAPOLBKMT2ATSHRCYP2D6 | |
| SCHEMBL9332848 | 0.92 | LMNA (0.52) | LMNAPOLBKMT2ATSHRCYP2D6 | |
| SCHEMBL29865166 | 0.92 | LMNA (0.52) | LMNAPOLBKMT2ATSHRCYP2D6 | |
| SCHEMBL8002809 | 0.84 | CYP3A4 (0.46) | LMNAPOLBKMT2ATSHRCYP2D6 | |
| SCHEMBL8831484 | 0.84 | LGALS3 (0.42) | LMNAPOLBKMT2ATSHRCYP2D6 | |
| SCHEMBL17456127 | 0.84 | NT5E (0.48) | LMNAPOLBKMT2ACYP2D6ALDH1A1 | |
| SCHEMBL17456128 | 0.84 | NT5E (0.48) | LMNAPOLBKMT2ACYP2D6ALDH1A1 | |
| SCHEMBL8831490 | 0.83 | LMNA (0.41) | LMNAPOLBKMT2ATSHRCYP2D6 | |
| SCHEMBL6553250 | 0.82 | TNF (0.42) | LMNAPOLBKMT2ATSHRCYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11673907-B2 | Modular synthesis of aminoglycosides | REVAGENIX, INC. (US) | 2023-06-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11673907-B2 | Modular synthesis of aminoglycosides | MRPL21, COASY, AARS1 | LMNA 2679/4885POLB 494/4885KMT2A 3736/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.