Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.68 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.68 |
| ▸ | CA2 | P00918 | 2/20 | 0.66 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.64 |
| ▸ | LMNA | P02545 | 2/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | NAMPT | P43490 | 3/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.58 |
| ▸ | CA1 | P00915 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 2/20 | 0.55 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.54 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.54 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.54 |
| ▸ | PRKCG | P05129 | 1/20 | 0.54 |
| ▸ | PRKACA | P17612 | 1/20 | 0.54 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | AKT1 | P31749 | 1/20 | 0.54 |
| ▸ | GSK3A | P49840 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23199278 | 0.94 | CA2 (0.74) | EPHX2NR1H4CA2LMNASMN1; SMN2 | |
| SCHEMBL933464 | 0.85 | ALDH1A1 (0.72) | EPHX2NR1H4CA2LMNACA1 | |
| SCHEMBL13658737 | 0.84 | NR1H4 (0.74) | EPHX2NR1H4CA2CA1GAA | |
| SCHEMBL933885 | 0.83 | TSHR (0.67) | EPHX2NR1H4CA2LMNANAMPT | |
| SCHEMBL12810429 | 0.82 | EPHX2 (0.72) | EPHX2NR1H4CA2L3MBTL1LMNA | |
| SCHEMBL1569157 | 0.82 | L3MBTL1 (0.77) | CA2L3MBTL1LMNASMN1; SMN2GAA | |
| SCHEMBL1568232 | 0.81 | SMN1; SMN2 (0.74) | L3MBTL1LMNASMN1; SMN2TDP1NAMPT | |
| SCHEMBL8374098 | 0.81 | L3MBTL1 (0.71) | CA2L3MBTL1LMNASMN1; SMN2CYP2C9 | |
| SCHEMBL19358856 | 0.81 | ALDH1A1 (0.76) | CA2LMNASMN1; SMN2TDP1NAMPT | |
| SCHEMBL22059471 | 0.81 | EPHX2 (1.00) | EPHX2NR1H4CA2L3MBTL1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011006935-A2 | TETRAZOLE DERIVATIVES | MERCK SERONO S.A. (CH) | 2011-01-20 | — | — | WO | disclosed |