Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.61 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.61 |
| ▸ | RAB9A | P51151 | 3/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | NPC1 | O15118 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | CASP3 | P42574 | 1/20 | 0.54 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.54 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.54 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.48 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9332113 | 0.84 | TSHR (0.53) | TSHRALOX15RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL9333325 | 0.80 | PDPK1 (0.52) | RAB9ASMN1; SMN2NPC1LMNATP53 | |
| SCHEMBL6864551 | 0.78 | NPC1 (0.56) | TSHRALOX15RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL28790754 | 0.78 | NPC1 (0.60) | TSHRALOX15RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL10510408 | 0.78 | ALDH1A1 (0.51) | TSHRALOX15RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL7476757 | 0.78 | ALOX15 (0.47) | TSHRALOX15RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL9332418 | 0.76 | TP53 (0.54) | TSHRRAB9ASMN1; SMN2NPC1LMNA | |
| SCHEMBL7469594 | 0.75 | LMNA (0.46) | TSHRALOX15RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL7532454 | 0.74 | RAB9A (0.46) | TSHRALOX15RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL11013469 | 0.74 | NPC1 (0.51) | TSHRALOX15RAB9ASMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0397169-B1 | Novel benzothiazole derivatives | TOYO BOSEKI (JP) | 1994-04-13 | — | — | EP | claimed |
| EP-0397169-A1 | Novel benzothiazole derivatives | TOYO BOSEKI KABUSHIKI KAISHA Trading under the name of Toyobo Co., Ltd. (JP) | 1990-11-14 | — | — | EP | claimed |
| JP-2300178-A | — | — | None | — | — | JP | disclosed |
| EP-0397169-B1 | Novel benzothiazole derivatives | TOYO BOSEKI (JP) | 1994-04-13 | — | — | EP | disclosed |
| US-5036086-A | Novel benzothiazole derivatives | TOYO BOSEKI KABUSHIKI KAISHA (JP) | 1991-07-30 | — | — | US | disclosed |
| JP-H02300178-A | NEW BENZOTHIAZOLE DERIVATIVE | TOYOBO CO LTD | 1990-12-12 | — | — | JP | disclosed |
| EP-0397169-A1 | Novel benzothiazole derivatives | TOYO BOSEKI KABUSHIKI KAISHA Trading under the name of Toyobo Co., Ltd. (JP) | 1990-11-14 | — | — | EP | disclosed |