Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TUBB1 | Q9H4B7 | 3/20 | 0.47 |
| ▸ | ESR1 | P03372 | 2/20 | 0.47 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.47 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.47 |
| ▸ | AHR | P35869 | 2/20 | 0.47 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.47 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.47 |
| ▸ | TUBB | P07437 | 2/20 | 0.47 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.47 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.47 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.47 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.47 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.47 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.47 |
| ▸ | TUBB8 | Q3ZCM7 | 2/20 | 0.47 |
| ▸ | TUBA3E | Q6PEY2 | 2/20 | 0.47 |
| ▸ | TUBA1A | Q71U36 | 2/20 | 0.47 |
| ▸ | TUBA1C | Q9BQE3 | 2/20 | 0.47 |
| ▸ | TUBB6 | Q9BUF5 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9333034 | 0.94 | TUBB1 (0.45) | TUBB1ESR1CYP1A1PTGS2CYP1B1 | |
| SCHEMBL9335469 | 0.86 | KDM4E (0.49) | PTGS2KDM4EPTGS1HSD11B1PKM | |
| SCHEMBL9332716 | 0.81 | KDM4E (0.47) | PTGS2KDM4EPTGS1HSD11B1PKM | |
| SCHEMBL5798973 | 0.74 | PTGS2 (0.60) | TUBB1ESR1CYP1A1PTGS2CYP1B1 | |
| SCHEMBL14345059 | 0.73 | PKM (0.59) | PTGS2LMNAHSD11B1PKMNPC1 | |
| SCHEMBL31420183 | 0.71 | PKM (0.52) | PTGS2NFE2L2HSD11B1PKMNPC1 | |
| SCHEMBL631998 | 0.71 | RELA (0.81) | TUBB1ESR1CYP1A1PTGS2CYP1B1 | |
| SCHEMBL13790336 | 0.71 | RELA (0.81) | TUBB1ESR1CYP1A1PTGS2CYP1B1 | |
| SCHEMBL4881152 | 0.71 | RELA (0.81) | TUBB1ESR1CYP1A1PTGS2CYP1B1 | |
| SCHEMBL699458 | 0.71 | RELA (0.81) | TUBB1ESR1CYP1A1PTGS2CYP1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0502955-B1 | FLUORINATED SULFONES/KETONES FOR NONLINEAR OPTICS | DU PONT (US) | 1994-08-03 | — | — | EP | disclosed |
| US-5312930-A | Useful in optical devices requiring second harmonic generation | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1994-05-17 | — | — | US | disclosed |
| US-5120876-A | FLUORINATED SULFONES/KETONES FOR NONLINEAR OPTICS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1992-06-09 | — | — | US | disclosed |
| WO-1991008198-A1 | FLUORINATED SULFONES/KETONES FOR NONLINEAR OPTICS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1991-06-13 | — | — | WO | disclosed |