Known targets — ChEMBL curated mechanism
CHRM1CHRM2CHRM3CHRM4CHRM5SLC6A2dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | SNCA | P37840 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | MMP1 | P03956 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | MMP9 | P14780 | 1/20 | 0.38 |
| ▸ | MMP8 | P22894 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9333537 | 0.93 | ALDH1A1 (0.46) | ALDH1A1SMN1; SMN2LMNATDP1KDM4E | |
| SCHEMBL8431688 | 0.91 | GAA (0.46) | ALDH1A1SMN1; SMN2LMNATDP1MAPT | |
| Sulfuric Acid SCHEMBL10539125 | 0.86 | GAA (0.43) | ALDH1A1SMN1; SMN2LMNATDP1MAPT | |
| SCHEMBL10337307 | 0.85 | TSHR (0.55) | ALDH1A1SMN1; SMN2LMNATDP1SNCA | |
| SCHEMBL26659522 | 0.84 | LMNA (0.50) | ALDH1A1SMN1; SMN2LMNATDP1KDM4E | |
| Potassium Ion SCHEMBL9548510 | 0.84 | LMNA (0.50) | ALDH1A1SMN1; SMN2LMNATDP1KDM4E | |
| SCHEMBL14862336 | 0.84 | LMNA (0.50) | ALDH1A1SMN1; SMN2LMNATDP1KDM4E | |
| SCHEMBL937040 | 0.84 | LMNA (0.52) | ALDH1A1SMN1; SMN2LMNATDP1KDM4E | |
| SCHEMBL336816 | 0.83 | CA12 (0.43) | ALDH1A1SMN1; SMN2LMNATDP1KDM4E | |
| Ammonia Solution, Strong SCHEMBL11068133 | 0.82 | LMNA (0.49) | ALDH1A1SMN1; SMN2LMNATDP1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0322882-B1 | Integral multilayer analytical element | FUJI PHOTO FILM CO LTD (JP) | 1994-05-18 | — | — | EP | disclosed |
| US-5215716-A | The fibers having roughed surface formed by alkali etching are superimposed by reagent layer and spreading layer; light-transmissive water-impermeable suppport; nondeforming, storage stability | FUJI PHOTO FILM CO., LTD. (JP) | 1993-06-01 | — | — | US | disclosed |
| EP-0134953-B1 | MULTILAYER ANALYTICAL ELEMENT | FUJI PHOTO FILM CO., LTD. (JP) | 1989-08-23 | — | — | EP | disclosed |
| EP-0322882-A2 | Integral multilayer analytical element | FUJI PHOTO FILM CO., LTD. (JP) | 1989-07-05 | — | — | EP | disclosed |
| US-4671937-A | DIAZONIUM SALT AND SULFONIC ACID GROUP-CONTAINING POLYMER | FUJI PHOTO FILM CO., LTD. (JP) | 1987-06-09 | — | — | US | disclosed |
| EP-0134953-A2 | Multilayer analytical element | FUJI PHOTO FILM CO., LTD. (JP) | 1985-03-27 | — | — | EP | disclosed |