Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | NT5E | P21589 | 1/20 | 0.38 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.35 |
| ▸ | SNCA | P37840 | 1/20 | 0.35 |
| ▸ | HTR6 | P50406 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | MMP1 | P03956 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | MMP9 | P14780 | 1/20 | 0.33 |
| ▸ | MMP8 | P22894 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10825103 | 0.87 | HTR6 (0.41) | TSHRSMN1; SMN2POLBALDH1A1TDP1 | |
| SCHEMBL937040 | 0.85 | LMNA (0.52) | TSHRSMN1; SMN2CYP2D6POLBLMNA | |
| SCHEMBL9333324 | 0.85 | ALDH1A1 (0.42) | TSHRSMN1; SMN2CYP2D6LMNAALDH1A1 | |
| SCHEMBL6740021 | 0.83 | TSHR (0.73) | TSHRSMN1; SMN2CYP2D6POLBLMNA | |
| SCHEMBL30041268 | 0.83 | TSHR (0.73) | TSHRSMN1; SMN2CYP2D6POLBLMNA | |
| Potassium Ion SCHEMBL28581538 | 0.83 | TSHR (0.73) | TSHRSMN1; SMN2CYP2D6POLBLMNA | |
| Hydrochloric Acid SCHEMBL3425485 | 0.83 | LMNA (0.50) | TSHRSMN1; SMN2CYP2D6POLBLMNA | |
| Water SCHEMBL3249386 | 0.83 | LMNA (0.50) | TSHRSMN1; SMN2CYP2D6POLBLMNA | |
| SCHEMBL1941777 | 0.83 | LMNA (0.37) | LMNATDP1 | |
| Ammonia Solution, Strong SCHEMBL11062653 | 0.81 | TSHR (0.70) | TSHRSMN1; SMN2CYP2D6POLBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-H791-H | MULTILAYER ANALYTICAL ELEMENT FOR QUANTITATIVE ANALYSIS OF BILIRUBIN | KATSUYAMA HARUMI (JP) | 1990-06-05 | — | — | US | disclosed |
| EP-0119861-B1 | MULTILAYER ANALYTICAL ELEMENT FOR QUANTITATIVE ANALYSIS OF BILIRUBIN | FUJI PHOTO FILM CO., LTD. (JP) | 1987-11-19 | — | — | EP | disclosed |
| EP-0119861-A1 | Multilayer analytical element for quantitative analysis of bilirubin | FUJI PHOTO FILM CO., LTD. (JP) | 1984-09-26 | — | — | EP | disclosed |