SCHEMBL9334263

SCHEMBL9334263

CCC1(S)C(=O)NC(=O)N(C)C1=O

nearest known ligand 0.46

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.46
ATM Q13315 1/20 0.43
TSHR P16473 1/20 0.36
CYP2C19 P33261 1/20 0.36
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9334290 0.84 LMNA (0.40) LMNAATMTSHRCYP2C19MEN1
SCHEMBL9337263 0.76 ATM (0.34) LMNAATMTSHRCYP2C19MEN1
Metharbital SCHEMBL78867 0.74 ATM (0.60) LMNAATMTSHRCYP2C19MEN1
SCHEMBL9337286 0.71 MEN1 (0.40) LMNAATMMEN1KMT2A
SCHEMBL9334278 0.70 LMNA (0.56) LMNATSHRCYP2C19
SCHEMBL9337194 0.69 ALDH1A1 (0.40) LMNATSHRCYP2C19MEN1KMT2A
SCHEMBL4618919 0.68 TSHR (0.44) LMNAATMTSHRCYP2C19
SCHEMBL200675 0.66 MEN1 (0.42) LMNAATMMEN1KMT2A
Metharbital SCHEMBL28086124 0.65 LMNA (0.55) LMNAATMTSHRCYP2C19KMT2A
SCHEMBL15461040 0.64 LMNA (0.39) LMNAATMMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5290172-A Method for preparing a tooth surface for bonding GC CORPORATION (JP) 1994-03-01 US disclosed