Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 9/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.60 |
| ▸ | MEN1 | O00255 | 5/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.60 |
| ▸ | MAPT | P10636 | 4/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.60 |
| ▸ | PPARG | P37231 | 2/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | TP53 | P04637 | 1/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.60 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.60 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.60 |
| ▸ | PKM | P14618 | 1/20 | 0.60 |
| ▸ | TSHR | P16473 | 1/20 | 0.60 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.60 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.60 |
| ▸ | THPO | P40225 | 1/20 | 0.60 |
| ▸ | MTOR | P42345 | 1/20 | 0.60 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20050377 | 0.85 | RORC (0.64) | RORCKMT2AMEN1SMN1; SMN2MAPT | |
| SCHEMBL4361418 | 0.83 | RORC (0.65) | RORCKMT2AMEN1SMN1; SMN2MAPT | |
| SCHEMBL7128741 | 0.81 | MAPT (0.82) | RORCKMT2AMEN1SMN1; SMN2MAPT | |
| SCHEMBL7465077 | 0.81 | RORC (0.55) | RORCKMT2AMEN1SMN1; SMN2MAPT | |
| SCHEMBL5396641 | 0.80 | L3MBTL1 (0.69) | RORCKMT2AMEN1SMN1; SMN2MAPT | |
| SCHEMBL7460757 | 0.80 | CYP1A2 (0.64) | RORCKMT2AMEN1SMN1; SMN2MAPT | |
| SCHEMBL4695652 | 0.79 | KMT2A (0.66) | RORCKMT2AMEN1SMN1; SMN2MAPT | |
| SCHEMBL7120601 | 0.79 | MAPT (0.77) | RORCKMT2AMEN1SMN1; SMN2MAPT | |
| SCHEMBL7597164 | 0.78 | RORC (0.59) | RORCKMT2AMEN1SMN1; SMN2MAPT | |
| SCHEMBL9334396 | 0.78 | RORC (0.52) | RORCKMT2AMEN1SMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0348826-B1 | Isobenzothiazolone chromogenic thiol indicators and their derivatives | MILES INC (US) | 1994-04-13 | — | — | EP | disclosed |
| US-5187265-A | Medical diagnosis | MILES INC. (US) | 1993-02-16 | — | — | US | disclosed |
| US-5187105-A | Process for determining thiols using chromogenic benzoisothiazolone derivatives | MILES INC. (US) | 1993-02-16 | — | — | US | disclosed |
| US-5130433-A | Indicators for detection of thiol | MILES INC. (US) | 1992-07-14 | — | — | US | disclosed |
| US-5128457-A | Medical diagnosis | MILES INC. (US) | 1992-07-07 | — | — | US | disclosed |
| EP-0348826-A2 | Isobenzothiazolone chromogenic thiol indicators and their derivatives | MILES INC. (US) | 1990-01-03 | — | — | EP | disclosed |