Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CBX7 | O95931 | 1/20 | 0.47 |
| ▸ | CDYL2 | Q8N8U2 | 1/20 | 0.47 |
| ▸ | CDYL | Q9Y232 | 1/20 | 0.47 |
| ▸ | PIM1 | P11309 | 1/20 | 0.47 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.47 |
| ▸ | RGS12 | O14924 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.43 |
| ▸ | WNT3A | P56704 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | GABRP | O00591 | 3/20 | 0.41 |
| ▸ | GABRD | O14764 | 3/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.41 |
| ▸ | GABRB1 | P18505 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9337520 | 0.86 | GPR84 (0.49) | PIM1GPR84TP53SMN1; SMN2NPSR1 | |
| SCHEMBL8793290 | 0.86 | ALDH1A1 (0.47) | CBX7CDYL2CDYLPIM1GPR84 | |
| SCHEMBL9334005 | 0.77 | KMT2A (0.59) | ALDH1A1MAPTHTTKMT2AHDAC3 | |
| SCHEMBL1367473 | 0.74 | HDAC6 (0.53) | HDAC3HDAC6 | |
| SCHEMBL9334431 | 0.74 | SRD5A1 (0.57) | KMT2A | |
| SCHEMBL9334424 | 0.73 | TRPA1 (0.55) | SMN1; SMN2MAPTHDAC3HDAC6RAB9A | |
| SCHEMBL21366213 | 0.73 | TP53 (0.55) | PIM1GPR84TP53SMN1; SMN2NPSR1 | |
| SCHEMBL22634965 | 0.72 | GPR84 (0.65) | PIM1GPR84TP53SMN1; SMN2NPSR1 | |
| SCHEMBL29988308 | 0.71 | GPR84 (0.79) | PIM1GPR84TP53SMN1; SMN2NPSR1 | |
| SCHEMBL3279652 | 0.71 | GPR84 (0.79) | PIM1GPR84TP53SMN1; SMN2NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5312829-A | Testosterone 5alpha-reductase inhibitors | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-05-17 | — | — | US | disclosed |
| US-5212320-A | Enzyme inhibitors | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-05-18 | — | — | US | disclosed |
| EP-0458207-A2 | Indole derivatives | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1991-11-27 | — | — | EP | disclosed |