Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.49 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.45 |
| ▸ | DHFR | P00374 | 1/20 | 0.45 |
| ▸ | F2 | P00734 | 1/20 | 0.44 |
| ▸ | PLG | P00747 | 1/20 | 0.44 |
| ▸ | PLAU | P00749 | 1/20 | 0.44 |
| ▸ | PLAT | P00750 | 1/20 | 0.44 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.44 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.44 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.44 |
| ▸ | RXRA | P19793 | 1/20 | 0.43 |
| ▸ | RXRB | P28702 | 1/20 | 0.43 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 3/20 | 0.42 |
| ▸ | ACACB | O00763 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.42 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.42 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.42 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL934347 | 0.88 | TAAR1 (0.66) | TAAR1ALDH1A1SMN1; SMN2 | |
| SCHEMBL934550 | 0.82 | EPHX1 (0.56) | TAAR1GRIN2B | |
| SCHEMBL19759404 | 0.82 | TAAR1 (0.71) | TAAR1DHFR | |
| SCHEMBL9935171 | 0.80 | TAAR1 (0.50) | TAAR1DHFRRXRARXRBP2RX3 | |
| SCHEMBL1416802 | 0.80 | TAAR1 (0.50) | TAAR1DHFRRXRARXRBP2RX3 | |
| SCHEMBL19766433 | 0.80 | SLC7A5 (0.59) | TAAR1KDM4E | |
| SCHEMBL5018939 | 0.80 | TAAR1 (0.53) | TAAR1DHFRRXRARXRBP2RX3 | |
| SCHEMBL24915424 | 0.79 | POLB (0.47) | TAAR1KDM4EALDH1A1POLB | |
| SCHEMBL934633 | 0.79 | GRIA2 (0.49) | TAAR1KDM4E | |
| SCHEMBL28662062 | 0.79 | ADRB2 (0.45) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011006935-A2 | TETRAZOLE DERIVATIVES | MERCK SERONO S.A. (CH) | 2011-01-20 | — | — | WO | disclosed |