Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.58 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.58 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 4/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | CA2 | P00918 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | MGLL | Q99685 | 5/20 | 0.46 |
| ▸ | FAAH | O00519 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11823867 | 0.91 | TXNRD1 (0.66) | TXNRD1TXNRD3TXNRD2MAPTALDH1A1 | |
| SCHEMBL10547907 | 0.85 | TXNRD1 (0.58) | TXNRD1TXNRD3TXNRD2MAPTALDH1A1 | |
| SCHEMBL832001 | 0.84 | ALDH1A1 (0.71) | TXNRD1TXNRD3TXNRD2MAPTALDH1A1 | |
| SCHEMBL6161726 | 0.82 | TXNRD1 (0.78) | TXNRD1TXNRD3TXNRD2MAPTALDH1A1 | |
| SCHEMBL30128616 | 0.82 | TXNRD1 (0.78) | TXNRD1TXNRD3TXNRD2MAPTALDH1A1 | |
| SCHEMBL11163992 | 0.80 | ALDH1A1 (0.40) | TXNRD1TXNRD3TXNRD2MAPTALDH1A1 | |
| SCHEMBL8442596 | 0.79 | TXNRD1 (0.72) | TXNRD1TXNRD3TXNRD2MAPTALDH1A1 | |
| SCHEMBL9287681 | 0.77 | TXNRD1 (0.55) | TXNRD1TXNRD3TXNRD2MAPTALDH1A1 | |
| SCHEMBL8442593 | 0.76 | TXNRD1 (0.68) | TXNRD1TXNRD3TXNRD2MAPTALDH1A1 | |
| SCHEMBL8379730 | 0.76 | TXNRD1 (0.68) | TXNRD1TXNRD3TXNRD2MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0348826-B1 | Isobenzothiazolone chromogenic thiol indicators and their derivatives | MILES INC (US) | 1994-04-13 | — | — | EP | disclosed |
| EP-0240849-B1 | Controlled hue test device | MILES INC (US) | 1993-11-24 | — | — | EP | disclosed |
| EP-0239926-B1 | RAINBOW TEST DEVICE | MILES INC. (US) | 1993-06-23 | — | — | EP | disclosed |
| US-5220035-A | Test compositions which generate different hues at different analyte concentrations | MILES INC. (US) | 1993-06-15 | — | — | US | disclosed |
| US-5187265-A | Medical diagnosis | MILES INC. (US) | 1993-02-16 | — | — | US | disclosed |
| US-5187105-A | Process for determining thiols using chromogenic benzoisothiazolone derivatives | MILES INC. (US) | 1993-02-16 | — | — | US | disclosed |
| US-5130433-A | Indicators for detection of thiol | MILES INC. (US) | 1992-07-14 | — | — | US | disclosed |
| US-5128457-A | Medical diagnosis | MILES INC. (US) | 1992-07-07 | — | — | US | disclosed |
| US-5041658-A | Indicator generates a variety of hues depending on the analyte concentration | MILES INC. (US) | 1991-08-20 | — | — | US | disclosed |
| US-4975367-A | Catalytic test composition intended to produce a range of colors | MILES INC. (US) | 1990-12-04 | — | — | US | disclosed |
| US-4898813-A | Catalytic test composition intended to produce a range of colors | MILES INC. | 1990-02-06 | — | — | US | disclosed |
| EP-0348826-A2 | Isobenzothiazolone chromogenic thiol indicators and their derivatives | MILES INC. (US) | 1990-01-03 | — | — | EP | disclosed |
| EP-0240849-A2 | Controlled hue test device | MILES INC. (US) | 1987-10-14 | — | — | EP | disclosed |
| EP-0239926-A2 | Rainbow test device | MILES INC. (US) | 1987-10-07 | — | — | EP | disclosed |