Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.40 |
| ▸ | HTR3B | O95264 | 1/20 | 0.40 |
| ▸ | HTR3A | P46098 | 1/20 | 0.40 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.40 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | GSK3B | P49841 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL145683 | 0.87 | ALDH1A1 (0.48) | ALDH1A1HPGDMAPTGAAKDM4E | |
| SCHEMBL15037449 | 0.79 | ALDH1A1 (0.44) | ALDH1A1HPGDMAPTGSK3BGAA | |
| SCHEMBL279706 | 0.78 | HTR3E (0.59) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL23611530 | 0.75 | ALDH1A1 (0.43) | ALDH1A1HPGDMAPTGAAKDM4E | |
| SCHEMBL30817926 | 0.75 | ALDH1A1 (0.43) | ALDH1A1HPGDMAPTGAAKDM4E | |
| SCHEMBL18562084 | 0.73 | KMT2A (0.37) | ALDH1A1HPGDMAPTMEN1KMT2A | |
| SCHEMBL145463 | 0.72 | ALDH1A1 (0.38) | ALDH1A1MAPTGAAKDM4EMEN1 | |
| SCHEMBL24855995 | 0.70 | ALDH1A1 (0.39) | ALDH1A1HPGDMAPTGAAKDM4E | |
| SCHEMBL23996294 | 0.70 | GSK3B (0.46) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL29360890 | 0.69 | ALDH1A1 (0.43) | ALDH1A1GAAKDM4EPTGS2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5286362-A | Reducible substance is enzymatically reduced and oxidized at the electrode; substance formed by oxidation is different from the reducible substance used initially | BOEHRINGER MANNHEIM GMBH (DE) | 1994-02-15 | — | — | US | claimed |