Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHR | P35869 | 1/20 | 0.46 |
| ▸ | PTGDR2 | Q9Y5Y4 | 8/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.38 |
| ▸ | TUBB | P07437 | 1/20 | 0.38 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.38 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.38 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.38 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.38 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.38 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.38 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.38 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.38 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.38 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.38 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.38 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.38 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.38 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9339138 | 0.81 | AHR (0.45) | AHRTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL9387728 | 0.79 | HSD17B10 (0.43) | AHRLMNAHDAC6DYRK1AMAOB | |
| SCHEMBL9338940 | 0.76 | MAPT (0.42) | LMNAHDAC6DYRK1AGAAMAOB | |
| SCHEMBL9335011 | 0.76 | AKR1B1 (0.40) | AHRLMNAPOLBDYRK1AMAOB | |
| SCHEMBL9337335 | 0.74 | KAT8 (0.51) | AHRTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL9337315 | 0.74 | KAT8 (0.51) | AHRTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL9389077 | 0.73 | MAPT (0.48) | ALDH1A1KDM4ELMNADYRK1AHCRTR1 | |
| SCHEMBL2908313 | 0.72 | PDE4A (0.50) | ALDH1A1KDM4EPOLBPKMGAA | |
| SCHEMBL9339063 | 0.72 | CYSLTR1 (0.36) | DYRK1AHCRTR1 | |
| SCHEMBL9388756 | 0.71 | HSD17B10 (0.38) | AHRCYP3A4HDAC6CYP2C9DYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0533695-B1 | IMIDAZO (4,5-c) PYRIDINES WITH PAF ANTAGONIST ACTIVITY | PFIZER (US) | 1994-10-05 | — | — | EP | disclosed |
| US-5322847-A | Inhibit platelet activating factor, block leukotriene D4 receptors | PFIZER INC. (US) | 1994-06-21 | — | — | US | disclosed |