Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHR | P35869 | 1/20 | 0.45 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | TNF | P01375 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.43 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.43 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.43 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9389077 | 0.83 | MAPT (0.48) | HCRTR1MAPTSMN1; SMN2KDM4EHPGD | |
| SCHEMBL9339038 | 0.81 | ALDH1A1 (0.50) | AHRHCRTR1MAPTSMN1; SMN2KDM4E | |
| SCHEMBL9337325 | 0.81 | AHR (0.46) | AHRHCRTR1KDM4ELMNAGAA | |
| SCHEMBL9339137 | 0.76 | KAT8 (0.50) | AHRHCRTR1MAPTSMN1; SMN2KDM4E | |
| SCHEMBL9385687 | 0.73 | MAPT (0.46) | MAPTSMN1; SMN2HPGDLMNAKMT2A | |
| SCHEMBL4300383 | 0.72 | SMN1; SMN2 (0.52) | MAPTSMN1; SMN2KDM4EHPGDLMNA | |
| SCHEMBL9387728 | 0.70 | HSD17B10 (0.43) | AHRMAPTSMN1; SMN2LMNAKMT2A | |
| SCHEMBL9337065 | 0.70 | PFKFB3 (0.47) | HCRTR1MAPTSMN1; SMN2KMT2AMEN1 | |
| SCHEMBL9335960 | 0.69 | DYRK1A (0.40) | HCRTR1MAPTSMN1; SMN2LMNAKMT2A | |
| SCHEMBL9339006 | 0.69 | MAPT (0.44) | AHRMAPTSMN1; SMN2KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5322847-A | Inhibit platelet activating factor, block leukotriene D4 receptors | PFIZER INC. (US) | 1994-06-21 | — | — | US | disclosed |