Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.52 |
| ▸ | LNPEP | Q9UIQ6 | 8/20 | 0.42 |
| ▸ | ERAP2 | Q6P179 | 7/20 | 0.42 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | MARS1 | P56192 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | ERAP1 | Q9NZ08 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Formic Acid SCHEMBL9335859 | 0.96 | POLB (0.48) | POLBLNPEPERAP2TLR7SMN1; SMN2 | |
| SCHEMBL9335895 | 0.88 | CASR (0.43) | POLBLNPEPERAP2MAPK1HTT | |
| Formic Acid SCHEMBL9339307 | 0.84 | CASR (0.43) | POLBLNPEPERAP2HTT | |
| SCHEMBL9337587 | 0.81 | HPGD (0.40) | POLBLNPEPERAP2HDAC1 | |
| SCHEMBL9335651 | 0.80 | EPHX2 (0.47) | GAA | |
| SCHEMBL12518601 | 0.78 | MMP2 (0.43) | POLB | |
| SCHEMBL12514977 | 0.78 | MMP2 (0.43) | POLB | |
| SCHEMBL9335939 | 0.78 | HDAC3 (0.39) | LNPEPERAP2SMN1; SMN2NPC1RAB9A | |
| SCHEMBL19445734 | 0.77 | ERAP2 (0.40) | LNPEPERAP2HDAC1HDAC6ERAP1 | |
| SCHEMBL13973836 | 0.77 | ERAP2 (0.40) | LNPEPERAP2HDAC1HDAC6ERAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0372486-B1 | Benzoic-acid phenylacetic-acid derivatives, their preparation and their use as medicines | HOFFMANN LA ROCHE (CH) | 1994-06-01 | — | — | EP | claimed |