Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.37 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.37 |
| ▸ | LNPEP | Q9UIQ6 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | NPY4R | P50391 | 5/20 | 0.36 |
| ▸ | NPY1R | P25929 | 4/20 | 0.36 |
| ▸ | NPY2R | P49146 | 4/20 | 0.36 |
| ▸ | NPY5R | Q15761 | 4/20 | 0.36 |
| ▸ | PPARG | P37231 | 2/20 | 0.36 |
| ▸ | GCGR | P47871 | 1/20 | 0.35 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.35 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9337587 | 0.88 | HPGD (0.40) | HDAC3HDAC1ITGB3ITGA2BLNPEP | |
| SCHEMBL9339324 | 0.87 | HDAC3 (0.35) | HDAC3HDAC1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL9335895 | 0.82 | CASR (0.43) | HDAC3ITGB3ITGA2BLNPEPERAP2 | |
| Formic Acid SCHEMBL9339307 | 0.79 | CASR (0.43) | HDAC3ITGB3ITGA2BLNPEPERAP2 | |
| SCHEMBL9337573 | 0.78 | POLB (0.52) | HDAC1NPC1RAB9ASMN1; SMN2LNPEP | |
| SCHEMBL9335889 | 0.77 | HDAC3 (0.35) | HDAC3HDAC1LNPEPNPY4RNPY1R | |
| SCHEMBL9335651 | 0.76 | EPHX2 (0.47) | ITGB3ITGA2BGAAGCGR | |
| SCHEMBL9866534 | 0.76 | GAA (0.46) | HDAC3HDAC1NPC1RAB9ASMN1; SMN2 | |
| Formic Acid SCHEMBL9335859 | 0.75 | POLB (0.48) | NPC1RAB9ASMN1; SMN2LNPEPERAP2 | |
| SCHEMBL12514977 | 0.75 | MMP2 (0.43) | NPY4RNPY1RNPY2RNPY5R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0372486-B1 | Benzoic-acid phenylacetic-acid derivatives, their preparation and their use as medicines | HOFFMANN LA ROCHE (CH) | 1994-06-01 | — | — | EP | claimed |