Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 6/20 | 0.38 |
| ▸ | MAOA | P21397 | 4/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 4/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.33 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9338105 | 0.82 | CYP2A6 (0.54) | ALDH1A1KMT2AKDM4EHPGDMAOB | |
| SCHEMBL9342014 | 0.81 | MAOB (0.51) | ALDH1A1KMT2AKDM4EHPGDMAOB | |
| SCHEMBL9339873 | 0.81 | P4HB (0.51) | MAOBMAOACYP2A6 | |
| SCHEMBL9338502 | 0.80 | ABCG2 (0.56) | ALDH1A1KMT2AKDM4EHPGDSMN1; SMN2 | |
| SCHEMBL9341522 | 0.78 | ALOX5 (0.49) | ALDH1A1KMT2AKDM4EHPGDMAOB | |
| SCHEMBL9341512 | 0.78 | MAOA (0.46) | ALDH1A1KMT2AKDM4EHPGDMAOB | |
| SCHEMBL9342531 | 0.77 | SMN1; SMN2 (0.38) | ALDH1A1KMT2AKDM4EHPGDMAOA | |
| SCHEMBL9342270 | 0.77 | SMN1; SMN2 (0.46) | ALDH1A1KMT2AKDM4EHPGDMAOB | |
| SCHEMBL9341962 | 0.77 | CYP2A6 (0.44) | ALDH1A1KMT2AKDM4EHPGDMAOB | |
| SCHEMBL9342232 | 0.77 | SMN1; SMN2 (0.44) | ALDH1A1KMT2AKDM4EHPGDMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0328668-B1 | NONLINEAR OPTICAL MATERIAL | NIPPON OILS & FATS CO LTD (JP) | 1994-05-25 | — | — | EP | disclosed |
| US-5045239-A | Chalcone derivative | NIPPON OIL AND FATS CO., LTD. (JP) | 1991-09-03 | — | — | US | disclosed |
| EP-0328668-A1 | NONLINEAR OPTICAL MATERIAL | NIPPON OIL AND FATS COMPANY, LIMITED (JP) | 1989-08-23 | — | — | EP | disclosed |