Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.51 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.50 |
| ▸ | APP | P05067 | 1/20 | 0.49 |
| ▸ | PDE4A | P27815 | 1/20 | 0.49 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9338012 | 0.86 | TUBB1 (0.65) | ABCG2KMT2AMEN1KDM4EMAPT | |
| SCHEMBL9342014 | 0.82 | MAOB (0.51) | KMT2AMEN1KDM4EMAPTLMNA | |
| SCHEMBL9338109 | 0.82 | ABCG2 (0.55) | ABCG2KMT2AMEN1NFE2L2MAPT | |
| SCHEMBL9337782 | 0.81 | CYP1A1 (0.45) | ABCG2KMT2AMEN1KDM4EMAPT | |
| SCHEMBL9338039 | 0.80 | ALDH1A1 (0.41) | ABCG2KMT2AMEN1KDM4EMAPT | |
| SCHEMBL9339939 | 0.80 | MAOB (0.54) | ABCG2KMT2AMEN1NFE2L2KDM4E | |
| SCHEMBL9342746 | 0.79 | ABCG2 (0.58) | ABCG2NFE2L2KDM4EMAPTLMNA | |
| SCHEMBL9341522 | 0.79 | ALOX5 (0.49) | KMT2AMEN1KDM4EMAPTLMNA | |
| SCHEMBL9341512 | 0.79 | MAOA (0.46) | KMT2AMEN1KDM4EMAPTLMNA | |
| SCHEMBL9341498 | 0.78 | TUBB1 (0.47) | ABCG2KMT2AMEN1LMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0328668-B1 | NONLINEAR OPTICAL MATERIAL | NIPPON OILS & FATS CO LTD (JP) | 1994-05-25 | — | — | EP | disclosed |
| US-5045239-A | Chalcone derivative | NIPPON OIL AND FATS CO., LTD. (JP) | 1991-09-03 | — | — | US | disclosed |
| EP-0328668-A1 | NONLINEAR OPTICAL MATERIAL | NIPPON OIL AND FATS COMPANY, LIMITED (JP) | 1989-08-23 | — | — | EP | disclosed |