Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | PLK1 | P53350 | 2/20 | 0.32 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.32 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
| ▸ | PPARA | Q07869 | 1/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.32 |
| ▸ | BACE1 | P56817 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9778593 | 0.88 | PTGS2 (0.38) | SMN1; SMN2ALDH1A1MAPTKMT2AMCHR1 | |
| SCHEMBL10499047 | 0.87 | THRA (0.44) | THRBKMT2A | |
| SCHEMBL9338556 | 0.86 | SMN1; SMN2 (0.42) | SMN1; SMN2ALOX5ALDH1A1NPC1MAPT | |
| SCHEMBL9341673 | 0.85 | SMN1; SMN2 (0.39) | SMN1; SMN2ALDH1A1THRBNPC1MAPT | |
| SCHEMBL10497881 | 0.80 | THRA (0.47) | THRBKMT2APLK1 | |
| SCHEMBL9338419 | 0.79 | SMN1; SMN2 (0.36) | SMN1; SMN2ALDH1A1THRBNPC1MAPT | |
| SCHEMBL9342184 | 0.79 | SMN1; SMN2 (0.41) | SMN1; SMN2ALOX5ALDH1A1THRBNPC1 | |
| SCHEMBL9341575 | 0.79 | MAOB (0.46) | SMN1; SMN2ALOX5ALDH1A1THRBNPC1 | |
| SCHEMBL9338680 | 0.78 | HDAC4 (0.39) | SMN1; SMN2CNR1CNR2ALDH1A1THRB | |
| SCHEMBL9339818 | 0.78 | MAOA (0.38) | SMN1; SMN2ALOX5ALDH1A1THRBNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0328668-B1 | NONLINEAR OPTICAL MATERIAL | NIPPON OILS & FATS CO LTD (JP) | 1994-05-25 | — | — | EP | disclosed |
| US-5045239-A | Chalcone derivative | NIPPON OIL AND FATS CO., LTD. (JP) | 1991-09-03 | — | — | US | disclosed |
| EP-0328668-A1 | NONLINEAR OPTICAL MATERIAL | NIPPON OIL AND FATS COMPANY, LIMITED (JP) | 1989-08-23 | — | — | EP | disclosed |