Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 6/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | HTT | P42858 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 3/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | AHR | P35869 | 1/20 | 0.46 |
| ▸ | CLK1 | P49759 | 1/20 | 0.44 |
| ▸ | CLK2 | P49760 | 1/20 | 0.44 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.43 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9389070 | 0.82 | KAT8 (0.48) | KAT8MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL9334957 | 0.82 | KAT8 (0.48) | KAT8MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL9337335 | 0.82 | KAT8 (0.51) | KAT8MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL9337315 | 0.82 | KAT8 (0.51) | KAT8MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL9339034 | 0.81 | PLA2G2A (0.45) | KAT8MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL9339042 | 0.81 | PLA2G2A (0.45) | KAT8MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL9339138 | 0.76 | AHR (0.45) | MAPTALDH1A1MEN1KMT2AHTT | |
| SCHEMBL13926056 | 0.74 | PTGS2 (0.59) | MAPTALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL4300383 | 0.73 | SMN1; SMN2 (0.52) | MAPTALDH1A1MEN1KMT2AHTT | |
| SCHEMBL23111746 | 0.72 | MEN1 (0.57) | MAPTALDH1A1MEN1KMT2AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5322847-A | Inhibit platelet activating factor, block leukotriene D4 receptors | PFIZER INC. (US) | 1994-06-21 | — | — | US | disclosed |