Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9339188 | 0.86 | GAA (0.53) | TSHRALDH1A1MAPK1NPSR1HDAC1 | |
| SCHEMBL9339094 | 0.78 | ALDH1A1 (0.52) | ALDH1A1KMT2AMEN1USP2LMNA | |
| SCHEMBL9339746 | 0.76 | SMN1; SMN2 (0.53) | TSHRALDH1A1KMT2AMEN1LMNA | |
| Methyl Nicotinate SCHEMBL29386553 | 0.76 | ALDH1A1 (1.00) | TSHRALDH1A1HPGDHDAC1HDAC6 | |
| Methyl Nicotinate SCHEMBL24566 | 0.76 | ALDH1A1 (1.00) | TSHRALDH1A1HPGDHDAC1HDAC6 | |
| Methyl Nicotinate SCHEMBL820747 | 0.76 | ALDH1A1 (1.00) | TSHRALDH1A1HPGDHDAC1HDAC6 | |
| Methyl Nicotinate SCHEMBL30779127 | 0.74 | ALDH1A1 (0.96) | TSHRALDH1A1HPGDHDAC1HDAC6 | |
| Methyl Nicotinate SCHEMBL29527047 | 0.74 | ALDH1A1 (0.96) | TSHRALDH1A1HPGDHDAC1HDAC6 | |
| Methyl Nicotinate SCHEMBL11491005 | 0.74 | ALDH1A1 (0.96) | TSHRALDH1A1HPGDHDAC1HDAC6 | |
| Methyl Nicotinate SCHEMBL28370871 | 0.74 | ALDH1A1 (0.96) | TSHRALDH1A1HPGDHDAC1HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5360808-A | Cardiovascular disorders, antispasmodic agents, hypotensive disorders, brains, anticonvulsants and antiepileptics | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-11-01 | — | — | US | disclosed |
| EP-0556738-A1 | Pyridinylcarbonylaminoalkyl-dihydro-oxo-pyridines, their production and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-08-25 | — | — | EP | disclosed |
| CN-1075480-A | New aryl carbonylamino alkyl-dihydro-oxo pyridine compounds and production thereof and application | HOECHST AG (US) | 1993-08-25 | — | — | CN | disclosed |