Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC29A1 | Q99808 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | SCN1A | P35498 | 2/20 | 0.36 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.36 |
| ▸ | SCN3A | Q9NY46 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9337972 | 0.81 | MAPT (0.41) | MAPTHTTKDM4EALDH1A1MEN1 | |
| SCHEMBL9729169 | 0.80 | ALDH1A1 (0.36) | MAPTHTTKDM4EALDH1A1MEN1 | |
| SCHEMBL9338356 | 0.76 | KDM4E (0.37) | MAPTHTTKDM4EALDH1A1MEN1 | |
| SCHEMBL27687891 | 0.70 | TNKS2 (0.57) | MEN1KMT2ATNKS2HTR2AHTR2B | |
| SCHEMBL7212713 | 0.69 | ACHE (0.45) | MAPTHTTKDM4EALDH1A1MEN1 | |
| SCHEMBL9339655 | 0.69 | TSHR (0.39) | MAPTHTTALDH1A1MEN1KMT2A | |
| SCHEMBL27788469 | 0.68 | KMT2A (0.55) | SLC29A1KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL12935903 | 0.67 | SMN1; SMN2 (0.41) | MAPTHTTKDM4EALDH1A1MEN1 | |
| SCHEMBL4472398 | 0.66 | PDE7A (0.52) | MAPTHTTKDM4EALDH1A1MEN1 | |
| Dimethylamine SCHEMBL9337974 | 0.65 | ALDH1A1 (0.40) | MAPTHTTKDM4EALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0450995-B1 | New propanamines, their pharmacological properties and their therapeutical applications, notably as anti-diarrhoea agents | JOUVEINAL SA (FR) | 1994-06-08 | — | — | EP | disclosed |
| US-5236947-A | Side effect reduction | JOUVEINAL S.A. (FR) | 1993-08-17 | — | — | US | disclosed |
| US-5143938-A | PROPANAMINES, THEIR PHARMACOLOGICAL PROPERTIES AND THEIR APPLICATION FOR THERAPEUTIC IN PARTICULAR ANTIDIARRHEAL, PURPOSES | JOUVEINAL S.A. (FR) | 1992-09-01 | — | — | US | disclosed |
| EP-0450995-A1 | New propanamines, their pharmacological properties and their therapeutical applications, notably as anti-diarrhoea agents | JOUVEINAL S.A. (FR) | 1991-10-09 | — | — | EP | disclosed |