Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 3/20 | 0.43 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.43 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.43 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | KDM5A | P29375 | 1/20 | 0.40 |
| ▸ | KDM1A | O60341 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9219845 | 0.78 | KIF11 (0.56) | KDM5AMEN1ALDH1A1MAPTALOX15 | |
| SCHEMBL9840137 | 0.77 | KDM5A (0.41) | SCN9ATRPA1SCN5AIDO1KDM5A | |
| SCHEMBL2803766 | 0.75 | KIF11 (0.57) | SCN9ATRPA1SCN5AKDM1AMAOB | |
| SCHEMBL28608366 | 0.75 | IDO1 (0.43) | SCN9ASCN5AIDO1NISCHALDH1A1 | |
| Hydrochloric Acid SCHEMBL4599674 | 0.74 | KIF11 (0.55) | SCN9ATRPA1SCN5AKDM1AMAOB | |
| SCHEMBL201174 | 0.73 | TRPA1 (0.53) | SCN9ATRPA1SCN5AKDM1AMAOB | |
| SCHEMBL7784781 | 0.72 | MCL1 (0.49) | MAOBMEN1ALDH1A1CYP3A4ALOX15 | |
| SCHEMBL9040621 | 0.72 | MAOA (0.47) | MAOBNISCHALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL1780240 | 0.71 | MCL1 (0.46) | MAOBALDH1A1TSHRTDP1NPC1 | |
| SCHEMBL12953430 | 0.71 | CYP11B1 (0.51) | PGRARKIF11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0347488-B1 | Arylpyrrole insecticidal acaricidal and nematicidal agents and method for the preparation thereof | AMERICAN CYANAMID CO (US) | 1994-06-01 | — | — | EP | disclosed |
| EP-0347488-A1 | Arylpyrrole insecticidal acaricidal and nematicidal agents and method for the preparation thereof | AMERICAN CYANAMID COMPANY (US) | 1989-12-27 | — | — | EP | disclosed |