Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 1/20 | 0.53 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.53 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.47 |
| ▸ | KIF11 | P52732 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2803766 | 0.94 | KIF11 (0.57) | TRPA1SCN5ASCN9AMAPTALDH1A1 | |
| SCHEMBL921865 | 0.94 | TRPA1 (0.49) | TRPA1SCN5ASCN9AMAPTALDH1A1 | |
| Hydrochloric Acid SCHEMBL4599674 | 0.92 | KIF11 (0.55) | TRPA1SCN5ASCN9AMAPTALDH1A1 | |
| SCHEMBL10435232 | 0.90 | MAOB (0.48) | TRPA1SCN5ASCN9AMAPTALDH1A1 | |
| SCHEMBL3464539 | 0.89 | TRPA1 (0.46) | TRPA1SCN5ASCN9AMAPTALDH1A1 | |
| SCHEMBL5470709 | 0.89 | DHODH (0.52) | TRPA1SCN5ASCN9AMAPTALDH1A1 | |
| SCHEMBL3464533 | 0.89 | TRPA1 (0.46) | TRPA1SCN5ASCN9AMAPTALDH1A1 | |
| SCHEMBL31739243 | 0.89 | CYP2A6 (0.47) | TRPA1SCN5ASCN9AMAPTALDH1A1 | |
| SCHEMBL489332 | 0.86 | ENPP2 (0.63) | TRPA1SCN5ASCN9AMAPTALDH1A1 | |
| SCHEMBL17338824 | 0.86 | EPHX2 (0.51) | TRPA1SCN5ASCN9AMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 266 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113024530-B | Isatin-1, 2, 4-oxadiazole compound and preparation method and application thereof | 合肥工业大学 | 2023-07-18 | — | — | CN | claimed |
| CN-111018780-B | N-carbonyl-9, 10-dihydroacridine compound and application thereof | 南方医科大学 | 2022-12-02 | — | — | CN | claimed |
| CN-113024530-A | Isatin-1, 2, 4-oxadiazole compound and preparation method and application thereof | 合肥工业大学 | 2021-06-25 | — | — | CN | claimed |
| CN-107750250-A | Indolone compounds and their use as ampa receptor modulators | 詹森药业有限公司 | 2018-03-02 | — | — | CN | claimed |
| US-8952083-B2 | Fluorocopolymer composition and its production process | ASAHI GLASS COMPANY, LIMITED (JP) | 2015-02-10 | — | — | US | claimed |
| WO-2005069000-A2 | METHODS OF IDENTIFYING CYTOTOXIC EFFECTS IN QUIESCENT CELLS | EISAI CO. LTD. (JP) | 2005-07-28 | — | — | WO | claimed |
| US-4822903-A | Fluorinated silica catalyst and preparation of aromatic/aliphatic nitriles in the presence thereof | RHONE-POULENC SPECIALITES CHIMIQUES (FR) | 1989-04-18 | — | — | US | claimed |
| US-4438042-A | FROM AMIDES, FLUORINATE SILCEOUS CATALYSTS | RHONE-POULENC SPECIALITES CHIMIQUES (FR) | 1984-03-20 | — | — | US | claimed |
| US-4436669-A | CYANATION, DECARBONYLATION, ACID CATALYSTS | RHONE-POULENC SPECIALITES CHIMIQUES (FR) | 1984-03-13 | — | — | US | claimed |
| US-20260001870-A1 | INHIBITOR COMPOUNDS | Cincera Therapeutics Pty Ltd (AU) | 2026-01-01 | — | — | US | disclosed |
| US-12448371-B2 | Inhibitor compounds | Cincera Therapeutics Pty Ltd (AU) | 2025-10-21 | — | — | US | disclosed |
| US-20250179008-A1 | ANTIBACTERIAL AGENTS | TAXIS PHARMACEUTICALS, INC. (US) | 2025-06-05 | — | — | US | disclosed |
| US-20250066370-A1 | BICYCLIC TRIAZINE DERIVATIVES FOR THE TREATMENT OF CANCER | DEUTSCHES KREBSFORSCH (DE) | 2025-02-27 | — | — | US | disclosed |
| CN-116375602-B | Method for photochemically synthesizing benzonitrile by using arylthianthrene salt | 河南大学 | 2024-10-18 | — | — | CN | disclosed |
| EP-0058424-A2 | Pyrazoline derivatives | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1982-08-25 | — | — | EP | disclosed |
| US-4318866-A | Chlorination of 4-methoxybenzoyl chloride | ELI LILLY AND COMPANY (US) | 1982-03-09 | — | — | US | disclosed |
| EP-0039157-A1 | Chlorination of 4-methoxybenzoyl chloride | ELI LILLY AND COMPANY (US) | 1981-11-04 | — | — | EP | disclosed |
| EP-0024888-A2 | Ketoximinoether insecticides | RHONE-POULENC INC. (US) | 1981-03-11 | — | — | EP | disclosed |
| US-4157344-A | REACTING PHENOLS WITH A PERHALOMETHANE AND HYDROGEN FLUORIDE | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1979-06-05 | — | — | US | disclosed |
| US-3994907-A | Coumarin derivatives, their preparation and their use as optical brightening agents | PRODUITS CHIMIQUES UGINE KUHLMANN (FR) | 1976-11-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250066370-A1 | BICYCLIC TRIAZINE DERIVATIVES FOR THE TREATMENT OF CANCER | BRCA1, CCNY, CCND2 | TRPA1 4645/4885SCN5A 1642/4885SCN9A 4793/4885 |
| US-20260001870-A1 | INHIBITOR COMPOUNDS | CES1, NCEH1, NR1H2 | TRPA1 4172/4885SCN5A 1510/4885SCN9A 1536/4885 |
| US-12448371-B2 | Inhibitor compounds | SERPINB1, MMP1, SSB | TRPA1 4787/4885SCN5A 3263/4885SCN9A 4045/4885 |
| US-20250179008-A1 | ANTIBACTERIAL AGENTS | ALK, ROS1, NOX1 | TRPA1 3164/4885SCN5A 1315/4885SCN9A 1697/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.