Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.65 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.65 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.65 |
| ▸ | TSHR | P16473 | 4/20 | 0.65 |
| ▸ | HPGD | P15428 | 4/20 | 0.65 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.65 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.65 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.65 |
| ▸ | CES2 | O00748 | 1/20 | 0.48 |
| ▸ | BCHE | P06276 | 1/20 | 0.48 |
| ▸ | CES1 | P23141 | 1/20 | 0.48 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.41 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Pyrene SCHEMBL5720270 | 0.82 | ALDH1A1 (0.65) | ALDH1A1HSD17B10CYP3A4TSHRHPGD | |
| Pyrene SCHEMBL9130 | 0.80 | ALDH1A1 (1.00) | ALDH1A1HSD17B10CYP3A4TSHRHPGD | |
| Pyrene SCHEMBL1332849 | 0.80 | ALDH1A1 (1.00) | ALDH1A1HSD17B10CYP3A4TSHRHPGD | |
| Pyrene SCHEMBL1650929 | 0.80 | ALDH1A1 (1.00) | ALDH1A1HSD17B10CYP3A4TSHRHPGD | |
| Pyrene SCHEMBL223412 | 0.80 | ALDH1A1 (1.00) | ALDH1A1HSD17B10CYP3A4TSHRHPGD | |
| Pyrene SCHEMBL29429699 | 0.80 | ALDH1A1 (1.00) | ALDH1A1HSD17B10CYP3A4TSHRHPGD | |
| Pyrene SCHEMBL28182630 | 0.78 | ALDH1A1 (0.79) | ALDH1A1HSD17B10CYP3A4TSHRHPGD | |
| Pyrene SCHEMBL2001417 | 0.78 | ALDH1A1 (0.79) | ALDH1A1HSD17B10CYP3A4TSHRHPGD | |
| Naphthalene SCHEMBL260764 | 0.78 | CYP2A6 (0.57) | ALDH1A1HSD17B10TSHRMEN1KMT2A | |
| SCHEMBL5917217 | 0.78 | ALDH1A1 (0.44) | ALDH1A1HSD17B10CYP3A4TSHRHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107098852-B | Di (2-methylpyridine) amine modified pyrene derivative fluorescent probe and synthetic method and application thereof | 陕西师范大学 | 2020-04-24 | — | — | CN | claimed |
| CN-104232077-A | Monopyrene fluorescent probe based on cholesterol modification, and synthesis method and application thereof | UNIV SHAANXI NORMAL | 2014-12-24 | — | — | CN | claimed |
| CN-102634334-A | Pyrene-dicholesterol-containing fluorescent probe, as well as synthetic method and application thereof | UNIV SHAANXI NORMAL | 2012-08-15 | — | — | CN | claimed |
| EP-0270651-B1 | NOVEL DEOXYRIBONUCLEOSIDE PHOSPHORAMIDITES AND THEIR USE FOR THE PREPARATION OF OLIGONUCLEOTIDES | CALIFORNIA INST OF TECHN (US) | 1994-06-15 | — | — | EP | claimed |
| US-5118802-A | DNA-reporter conjugates linked via the 2' or 5'-primary amino group of the 5'-terminal nucleoside | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 1992-06-02 | — | — | US | claimed |
| EP-0270651-A4 | NOVEL DEOXYRIBONUCLEOSIDE PHOSPHORAMIDITES AND THEIR USE FOR THE PREPARATION OF OLIGONUCLEOTIDES. | CALIFORNIA INST OF TECHN (US) | 1989-03-29 | — | — | EP | claimed |
| EP-0270651-A1 | NOVEL DEOXYRIBONUCLEOSIDE PHOSPHORAMIDITES AND THEIR USE FOR THE PREPARATION OF OLIGONUCLEOTIDES. | CALIFORNIA INST OF TECHN (US) | 1988-06-15 | — | — | EP | claimed |
| WO-1988000201-A1 | NOVEL DEOXYRIBONUCLEOSIDE PHOSPHORAMIDITES AND THEIR USE FOR THE PREPARATION OF OLIGONUCLEOTIDES | CALIFORNIA INSTITUTE OF TECHNOLOGY, INC. (US) | 1988-01-14 | — | — | WO | claimed |
| CN-107098852-B | Di (2-methylpyridine) amine modified pyrene derivative fluorescent probe and synthetic method and application thereof | 陕西师范大学 | 2020-04-24 | — | — | CN | disclosed |
| CN-104232077-A | Monopyrene fluorescent probe based on cholesterol modification, and synthesis method and application thereof | UNIV SHAANXI NORMAL | 2014-12-24 | — | — | CN | disclosed |
| CN-102634334-B | Pyrene-dicholesterol-containing fluorescent probe, as well as synthetic method and application thereof | UNIV SHAANXI NORMAL | 2014-12-10 | — | — | CN | disclosed |
| CN-102634334-A | Pyrene-dicholesterol-containing fluorescent probe, as well as synthetic method and application thereof | UNIV SHAANXI NORMAL | 2012-08-15 | — | — | CN | disclosed |
| EP-0270651-B1 | NOVEL DEOXYRIBONUCLEOSIDE PHOSPHORAMIDITES AND THEIR USE FOR THE PREPARATION OF OLIGONUCLEOTIDES | CALIFORNIA INST OF TECHN (US) | 1994-06-15 | — | — | EP | disclosed |
| US-5118800-A | Oligonucleotides possessing a primary amino group in the terminal nucleotide | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 1992-06-02 | — | — | US | disclosed |
| US-5118802-A | DNA-reporter conjugates linked via the 2' or 5'-primary amino group of the 5'-terminal nucleoside | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 1992-06-02 | — | — | US | disclosed |
| US-5015733-A | Phosphoramidites and oligonucleotides derived therefrom | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 1991-05-14 | — | — | US | disclosed |
| US-4849513-A | Deoxyribonucleoside phosphoramidites in which an aliphatic amino group is attached to the sugar ring and their use for the preparation of oligonucleotides containing aliphatic amino groups | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 1989-07-18 | — | — | US | disclosed |
| EP-0270651-A4 | NOVEL DEOXYRIBONUCLEOSIDE PHOSPHORAMIDITES AND THEIR USE FOR THE PREPARATION OF OLIGONUCLEOTIDES. | CALIFORNIA INST OF TECHN (US) | 1989-03-29 | — | — | EP | disclosed |
| EP-0270651-A1 | NOVEL DEOXYRIBONUCLEOSIDE PHOSPHORAMIDITES AND THEIR USE FOR THE PREPARATION OF OLIGONUCLEOTIDES. | CALIFORNIA INST OF TECHN (US) | 1988-06-15 | — | — | EP | disclosed |
| WO-1988000201-A1 | NOVEL DEOXYRIBONUCLEOSIDE PHOSPHORAMIDITES AND THEIR USE FOR THE PREPARATION OF OLIGONUCLEOTIDES | CALIFORNIA INSTITUTE OF TECHNOLOGY, INC. (US) | 1988-01-14 | — | — | WO | disclosed |