Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY1 | P47900 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | NPY5R | Q15761 | 4/20 | 0.39 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.38 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.36 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.35 |
| ▸ | STS | P08842 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9341239 | 0.76 | PDK1 (0.33) | P2RY1L3MBTL1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL427069 | 0.76 | NOTUM (0.43) | SMN1; SMN2GAAMAPTMEN1ALDH1A1 | |
| SCHEMBL449911 | 0.75 | NOTUM (0.40) | P2RY1SMN1; SMN2GAAMAPTMEN1 | |
| SCHEMBL450748 | 0.72 | AKR1B1 (0.46) | L3MBTL1MAPTMEN1ALDH1A1KMT2A | |
| SCHEMBL9129687 | 0.68 | TRPV1 (0.36) | P2RY1SMN1; SMN2CYP2C9MAPTMEN1 | |
| SCHEMBL7413801 | 0.68 | LMNA (0.57) | SMN1; SMN2MAPTNPC1ALDH1A1RAB9A | |
| SCHEMBL8518362 | 0.67 | CYP1A2 (0.48) | L3MBTL1SMN1; SMN2GAACYP1A2CYP2C9 | |
| SCHEMBL13757245 | 0.66 | MAPKAPK2 (0.41) | P2RY1L3MBTL1SMN1; SMN2MAPTMEN1 | |
| SCHEMBL9341296 | 0.66 | NOTUM (0.36) | — | |
| SCHEMBL27399714 | 0.66 | SMN1; SMN2 (0.47) | L3MBTL1SMN1; SMN2GAACYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5278158-A | Heteropolycyclic pyridyl or pyridyl oxide | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1994-01-11 | — | — | US | disclosed |
| EP-0500319-A1 | Oxazinobenzazole compounds | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1992-08-26 | — | — | EP | disclosed |