Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.78 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.58 |
| ▸ | MAPT | P10636 | 4/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.50 |
| ▸ | CES2 | O00748 | 1/20 | 0.46 |
| ▸ | CES1 | P23141 | 1/20 | 0.46 |
| ▸ | MITF | O75030 | 1/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10844950 | 0.88 | ALDH1A1 (1.00) | ALDH1A1SMN1; SMN2MAPTMEN1KMT2A | |
| SCHEMBL2434292 | 0.81 | NR4A1 (0.61) | ALDH1A1SMN1; SMN2MAPTNR4A1NPSR1 | |
| SCHEMBL9336033 | 0.81 | ALDH1A1 (0.49) | ALDH1A1SMN1; SMN2MAPTMEN1KMT2A | |
| SCHEMBL19604507 | 0.80 | SMN1; SMN2 (0.89) | ALDH1A1SMN1; SMN2MAPTMEN1KMT2A | |
| SCHEMBL27634042 | 0.79 | ALDH1A1 (0.81) | ALDH1A1SMN1; SMN2MAPTMEN1KMT2A | |
| SCHEMBL9346174 | 0.77 | TUBB4A (0.52) | ALDH1A1SMN1; SMN2MAPTNR4A1NPSR1 | |
| SCHEMBL19599377 | 0.77 | ALDH1A1 (0.66) | ALDH1A1SMN1; SMN2MAPTMEN1KMT2A | |
| SCHEMBL10953514 | 0.75 | RAB9A (0.67) | ALDH1A1SMN1; SMN2MAPTMEN1KMT2A | |
| SCHEMBL30114756 | 0.75 | NR4A1 (0.85) | ALDH1A1MAPTMAPK1NR4A1NPSR1 | |
| SCHEMBL28451754 | 0.75 | NR4A1 (0.85) | ALDH1A1MAPTMAPK1NR4A1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5318983-A | Fungicides and bactericides having broad spectrum activity to mycetes and Grampositive and Gramnegative bacteria | APR APPLIED PHARMA RESEARCH S.A. (CH) | 1994-06-07 | — | — | US | disclosed |
| EP-0569575-A1 | TRISUBSTITUTED PYRROLE DERIVATIVES HAVING ANTIFUNGINE ACTIVITY, A PROCESS FOR THEIR PREPARATION AND RELATED PHARMACEUTICAL COMPOSITIONS | APR APPLIED PHARMA RESEARCH S.A. (CH) | 1993-11-18 | — | — | EP | disclosed |
| WO-1993011124-A1 | TRISUBSTITUTED PYRROLE DERIVATIVES HAVING ANTIFUNGINE ACTIVITY, A PROCESS FOR THEIR PREPARATION AND RELATED PHARMACEUTICAL COMPOSITIONS | APR APPLIED PHARMA RESEARCH S.A. (CH) | 1993-06-10 | — | — | WO | disclosed |