Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TUBB4A | P04350 | 3/20 | 0.52 |
| ▸ | TUBB | P07437 | 3/20 | 0.52 |
| ▸ | TUBA3C | P0DPH7 | 3/20 | 0.52 |
| ▸ | TUBA1B | P68363 | 3/20 | 0.52 |
| ▸ | TUBA4A | P68366 | 3/20 | 0.52 |
| ▸ | TUBB4B | P68371 | 3/20 | 0.52 |
| ▸ | TUBB3 | Q13509 | 3/20 | 0.52 |
| ▸ | TUBB2A | Q13885 | 3/20 | 0.52 |
| ▸ | TUBB8 | Q3ZCM7 | 3/20 | 0.52 |
| ▸ | TUBA3E | Q6PEY2 | 3/20 | 0.52 |
| ▸ | TUBA1A | Q71U36 | 3/20 | 0.52 |
| ▸ | TUBA1C | Q9BQE3 | 3/20 | 0.52 |
| ▸ | TUBB6 | Q9BUF5 | 3/20 | 0.52 |
| ▸ | TUBB2B | Q9BVA1 | 3/20 | 0.52 |
| ▸ | TUBB1 | Q9H4B7 | 3/20 | 0.52 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.47 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | CNR2 | P34972 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27653961 | 0.81 | ALDH1A1 (0.44) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL2434292 | 0.78 | NR4A1 (0.61) | NR4A1MAPK14ALDH1A1NPC1RAB9A | |
| SCHEMBL9341973 | 0.77 | ALDH1A1 (0.78) | NR4A1MAPK14ALDH1A1CNR2NPC1 | |
| SCHEMBL23147093 | 0.76 | NPC1 (0.44) | NR4A1ALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL11551182 | 0.74 | CYP1A2 (0.48) | ALDH1A1NPC1RAB9ASMN1; SMN2HTT | |
| SCHEMBL9343573 | 0.73 | MAPT (0.48) | NR4A1MAPK14ALDH1A1CNR2NPC1 | |
| SCHEMBL28451754 | 0.71 | NR4A1 (0.85) | NR4A1ALDH1A1ATMNPSR1CYP2C9 | |
| SCHEMBL10953514 | 0.71 | RAB9A (0.67) | NR4A1ALDH1A1CNR2NPC1RAB9A | |
| SCHEMBL30114756 | 0.71 | NR4A1 (0.85) | NR4A1ALDH1A1ATMNPSR1CYP2C9 | |
| SCHEMBL27560518 | 0.71 | FNTA (0.48) | ALDH1A1CNR2SMN1; SMN2HTTATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5318983-A | Fungicides and bactericides having broad spectrum activity to mycetes and Grampositive and Gramnegative bacteria | APR APPLIED PHARMA RESEARCH S.A. (CH) | 1994-06-07 | — | — | US | disclosed |
| EP-0569575-A1 | TRISUBSTITUTED PYRROLE DERIVATIVES HAVING ANTIFUNGINE ACTIVITY, A PROCESS FOR THEIR PREPARATION AND RELATED PHARMACEUTICAL COMPOSITIONS | APR APPLIED PHARMA RESEARCH S.A. (CH) | 1993-11-18 | — | — | EP | disclosed |
| WO-1993011124-A1 | TRISUBSTITUTED PYRROLE DERIVATIVES HAVING ANTIFUNGINE ACTIVITY, A PROCESS FOR THEIR PREPARATION AND RELATED PHARMACEUTICAL COMPOSITIONS | APR APPLIED PHARMA RESEARCH S.A. (CH) | 1993-06-10 | — | — | WO | disclosed |