Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 8/20 | 0.66 |
| ▸ | FAAH | O00519 | 3/20 | 0.58 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.56 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.53 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.53 |
| ▸ | GLS | O94925 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | CNR1 | P21554 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17335666 | 0.96 | EPHX2 (0.72) | EPHX2FAAHMAPK14CNR1 | |
| SCHEMBL3638883 | 0.92 | EPHX2 (0.58) | EPHX2FAAHMAPK14ROCK2ROCK1 | |
| SCHEMBL934551 | 0.87 | GLS (0.61) | EPHX2MAPK14ROCK2ROCK1GLS | |
| SCHEMBL7366428 | 0.86 | EPHX2 (0.58) | EPHX2FAAHMAPK14ROCK2ROCK1 | |
| SCHEMBL934356 | 0.84 | HPGD (0.65) | EPHX2HPGDCNR1 | |
| SCHEMBL934606 | 0.84 | EPHX2 (0.90) | EPHX2FAAHCNR1 | |
| SCHEMBL30229536 | 0.83 | MAPK14 (0.54) | EPHX2MAPK14ROCK2ROCK1GLS | |
| SCHEMBL5724446 | 0.81 | MAPK14 (0.63) | MAPK14ROCK2ROCK1GLSCNR1 | |
| SCHEMBL14684325 | 0.81 | MAPK14 (0.59) | MAPK14ROCK2ROCK1GLSCNR1 | |
| SCHEMBL26051588 | 0.80 | MAPK14 (0.53) | EPHX2MAPK14ROCK2ROCK1GLS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011006935-A2 | TETRAZOLE DERIVATIVES | MERCK SERONO S.A. (CH) | 2011-01-20 | — | — | WO | disclosed |