Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.61 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL259951 | 0.86 | ALDH1A1 (0.52) | ALDH1A1KMT2AKDM4EMAPTTSHR | |
| SCHEMBL30047263 | 0.86 | ALDH1A1 (0.52) | ALDH1A1KMT2AKDM4EMAPTTSHR | |
| SCHEMBL15519819 | 0.83 | KMT2A (0.56) | ALDH1A1KMT2AKDM4EMAPTTSHR | |
| SCHEMBL8911487 | 0.83 | KMT2A (0.56) | ALDH1A1KMT2AKDM4EMAPTTSHR | |
| SCHEMBL15774873 | 0.82 | KMT2A (0.64) | ALDH1A1KMT2AKDM4EMAPTMAPK1 | |
| SCHEMBL9300629 | 0.80 | ALDH1A1 (0.69) | ALDH1A1KMT2AKDM4EMAPTMAPK1 | |
| SCHEMBL11200246 | 0.78 | CYP1A2 (0.49) | ALDH1A1MAPTMAPK1ATMTSHR | |
| SCHEMBL15116647 | 0.78 | ACHE (0.46) | ALDH1A1MAPTTSHRHSD17B10 | |
| SCHEMBL490810 | 0.78 | MAPT (0.70) | ALDH1A1KMT2AKDM4EMAPTMAPK1 | |
| SCHEMBL31460799 | 0.78 | MAPT (0.70) | ALDH1A1KMT2AKDM4EMAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5292768-A | Compound effective as cerebral insufficiency improver | SUNTORY LIMITED (JP) | 1994-03-08 | — | — | US | disclosed |
| US-5288752-A | Brain disorders | SUNTORY LIMITED (JP) | 1994-02-22 | — | — | US | disclosed |
| EP-0322248-B1 | COMPOUNDS EFFECTIVE AGAINST CEREBRAL INSUFFICIENCY | SUNTORY LIMITED (JP) | 1993-08-04 | — | — | EP | disclosed |
| US-5179092-A | Cognition activators | SUNTORY LIMITED (JP) | 1993-01-12 | — | — | US | disclosed |
| US-5057514-A | Compounds effective as cerebral schemia treating agents | SUNTORY LIMITED (JP) | 1991-10-15 | — | — | US | disclosed |
| EP-0322248-A2 | Compounds effective against cerebral insufficiency | SUNTORY LIMITED (JP) | 1989-06-28 | — | — | EP | disclosed |