Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.38 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.38 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9344930 | 0.92 | MAPT (0.40) | MAPTALDH1A1HPGDCYP3A4KEAP1 | |
| SCHEMBL9348914 | 0.92 | MAPT (0.40) | MAPTALDH1A1HPGDCYP3A4KEAP1 | |
| SCHEMBL9696240 | 0.86 | CYP3A4 (0.43) | MAPTALDH1A1HPGDCYP3A4TSHR | |
| SCHEMBL9345469 | 0.85 | ELANE (0.40) | MAPTALDH1A1HPGDCYP3A4TSHR | |
| SCHEMBL9695986 | 0.83 | MAPT (0.43) | MAPTALDH1A1HPGDCYP3A4KMT2A | |
| SCHEMBL10438176 | 0.83 | KMT2A (0.34) | MAPTALDH1A1CYP3A4KEAP1NFE2L2 | |
| SCHEMBL21462592 | 0.82 | MEN1 (0.40) | MAPTALDH1A1HPGDCYP3A4KMT2A | |
| SCHEMBL11286854 | 0.80 | POLB (0.43) | ALDH1A1CYP3A4KMT2ALMNAPOLB | |
| SCHEMBL9695990 | 0.79 | RAB9A (0.43) | MAPTALDH1A1HPGDCYP3A4KMT2A | |
| SCHEMBL2790849 | 0.79 | CYP3A4 (0.51) | MAPTALDH1A1HPGDCYP3A4TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0393782-B1 | Catecholamine esters | ZAMBON SPA (IT) | 1994-08-03 | — | — | EP | disclosed |
| US-5144059-A | CATECHOLAMINE ESTERS | SIMES SOCIETA ITALIANA MEDICINALI E. SINTETICI S.A. (IT) | 1992-09-01 | — | — | US | disclosed |