Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.38 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.38 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.36 |
| ▸ | DRD1 | P21728 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9348914 | 1.00 | MAPT (0.40) | MAPTALOX15ALDH1A1HPGDKEAP1 | |
| SCHEMBL9696240 | 0.93 | CYP3A4 (0.43) | MAPTALOX15ALDH1A1HPGDADRB2 | |
| SCHEMBL9345469 | 0.93 | ELANE (0.40) | MAPTALOX15ALDH1A1HPGDADRB2 | |
| SCHEMBL9344950 | 0.92 | MAPT (0.40) | MAPTALDH1A1HPGDKEAP1NFE2L2 | |
| SCHEMBL9696041 | 0.84 | MAPT (0.41) | MAPTALOX15ALDH1A1HPGDADRB2 | |
| SCHEMBL9696537 | 0.84 | MAPT (0.41) | MAPTALOX15ALDH1A1HPGDADRB2 | |
| SCHEMBL10438192 | 0.82 | ALOX15 (0.36) | MAPTALOX15ALDH1A1KEAP1NFE2L2 | |
| SCHEMBL9696017 | 0.82 | CA1 (0.39) | ALOX15ALDH1A1ADRB2ADRA2ADRD2 | |
| SCHEMBL21462592 | 0.82 | MEN1 (0.40) | MAPTALDH1A1HPGDADRB2CYP3A4 | |
| SCHEMBL9696046 | 0.81 | ALOX15 (0.43) | MAPTALOX15ALDH1A1HPGDADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0393782-B1 | Catecholamine esters | ZAMBON SPA (IT) | 1994-08-03 | — | — | EP | disclosed |
| US-5144059-A | CATECHOLAMINE ESTERS | SIMES SOCIETA ITALIANA MEDICINALI E. SINTETICI S.A. (IT) | 1992-09-01 | — | — | US | disclosed |