Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.38 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.37 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9695990 | 0.92 | RAB9A (0.43) | MAPTALDH1A1HPGDKMT2APKM | |
| SCHEMBL9696041 | 0.90 | MAPT (0.41) | MAPTALDH1A1HPGDKMT2ANPC1 | |
| SCHEMBL9696537 | 0.90 | MAPT (0.41) | MAPTALDH1A1HPGDKMT2ANPC1 | |
| SCHEMBL9696955 | 0.88 | MAPT (0.44) | MAPTALDH1A1HPGDKMT2ANPC1 | |
| SCHEMBL9694915 | 0.85 | MAPT (0.42) | MAPTALDH1A1HPGDKMT2APKM | |
| SCHEMBL9696523 | 0.85 | MAPT (0.42) | MAPTALDH1A1HPGDKMT2APKM | |
| SCHEMBL23040671 | 0.83 | HPGD (0.44) | MAPTALDH1A1HPGDKMT2ANPC1 | |
| SCHEMBL9344950 | 0.83 | MAPT (0.40) | MAPTALDH1A1HPGDKMT2APKM | |
| SCHEMBL9696046 | 0.83 | ALOX15 (0.43) | MAPTALDH1A1HPGDKMT2ANPC1 | |
| SCHEMBL9696544 | 0.83 | ALOX15 (0.43) | MAPTALDH1A1HPGDKMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5144059-A | CATECHOLAMINE ESTERS | SIMES SOCIETA ITALIANA MEDICINALI E. SINTETICI S.A. (IT) | 1992-09-01 | — | — | US | disclosed |